Basic information
- Name:
Ichthammol
- CAS No.:
8029-68-3
- Synonyms:
- Albichthol;Albichtol;Albikhtol;Ammonium bithiolicum;Ammonium bituminosulfonate;Ammonium ichthosulfonate;Ammonium ichthyolate;Ammonium sulfobituminate;Ammonium sulfoichthyolate;Amsubit;Bitulan;Bituminol;Bitumol;Hirathiol;Ichden;Ichtammon;Ichthadone;Ichthalum;Ichthammonium;Ichthium;Ichthosan;Ichthosauran;Ichthosulfol;Ichthymall;Ichthyn;Ichthynat;Ichthyol;Ichthyolsulfonic acid, ammonium salt;Ichthyopon;Ichthysalle;Ichtopur;Leukochthol;Lithol;Perichthol;Petrosulpho;Piscarol;Pisciol;Saurol;Subitol;Sulfogenol;Sulfoichthyolic acid, ammonium salt;Thilaven;Thiolin;Thiosept;Thiozin;Trasulphane;Tumenol;
- EINECS:
- 232-439-0
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Chemistry
Product Name: Ichthammol (CAS NO.8029-68-3)
Mol File: 8029-68-3.mol
EINECS: 232-439-0
Classification Code: Anti-infective, topical ; Drug / Therapeutic Agent ; Human Data
Uses
Ichthammol (CAS NO.8029-68-3) is used in medicine as a remedy for treating some forms of skin diseases, such as acne, eczema and psoriasis.And it is also commonly used in an ointment in 10% or 20% concentrate as a "drawing salve", also called "black ointment".
Production
Ichthammol can be presented in two forms: pale sulfonated shale oil (PSSO), and dark sulfonated shale oil (DSSO).
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 700mg/kg (700mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 6, Pg. 199, 1956. | |
| rabbit | LDLo | intravenous | 1gm/kg (1000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 6, Pg. 199, 1956. | |
| rat | LD | oral | > 10gm/kg (10000mg/kg) | BEHAVIORAL: ATAXIA | Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 844, 1994. |
| rat | LD | skin | > 21500mg/kg (21500mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 844, 1994. | |
| women | LDLo | oral | 125mg/kg (125mg/kg) | BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA GASTROINTESTINAL: NAUSEA OR VOMITING | Annales de Medecine Legale et de Criminologie. Vol. 37, Pg. 248, 1957. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
A human poison which causes these systemic effects: nausea, acute pulminary edema, coma. An FDA over-the-counter drug. When heated to decomposition it emits very toxic fumes of NH3, NOx, and SOx.
Specification
Ichthammol , its CAS NO. is 8029-68-3, the synonyms are Ammonii bituminosulfonat ; Ammonium bithiolicum ; Ammonium ichthosulfonate ; Ammonium sulfobituminosum ; Ammonium sulfoichthyolate ; Ammoniumbituminosulfonat ; Ammoniumbituminosulfonate DAB ; Amsubit ; Bitumenschieferdestillat solfoniertes ; Bitumol ; EPA Pesticide Chemical Code 046401 ; Fungichthol ; Hirathiol ; Ichden ; Ichtammon ; Ichthadone ; Ichthalum ; Ichthium ; Ichthosan ; Ichthosauran ; Ichthosulfol ; Ichthymall ; Ichthynat ; Ichthyol ; Ichthyopon ; Ichthysalle ; Icthymall ; Icthyol ; Leukichthol ; Lithol ; Perichthol ; Petrosulpho ; Piscarol ; Pisciol ; Saurol ; Subitol ; Sulfogenol ; Thilaven ; Thiolin ; Thiozin ; Trasulphane ; Tumenol .