Basic Information | Post buying leads | Suppliers |
Name |
Ketamine |
EINECS | N/A |
CAS No. | 33643-45-7 | Density | N/A |
PSA | N/A | LogP | N/A |
Solubility | N/A | Melting Point |
N/A |
Formula | C13H16ClNO | Boiling Point | N/A |
Molecular Weight | N/A | Flash Point | N/A |
Transport Information | N/A | Appearance | N/A |
Safety | Risk Codes | N/A | |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
N/A |
Ketamine, with the CAS NO.33643-45-7, is also named as 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone; (+-)-Ketamine; 2-(Methylamino)-2-(2-chlorophenyl)cyclohexanone; 2-(o-Chlorophenyl)-2-(methylamino)-cyclohexanone. Ketamine is a drug used in human and veterinary medicine, primarily for the induction and maintenance of general anesthesia, usually in combination with a sedative. Ketamine is odorless and tasteless, so it can be added to beverages without being detected, and it induces amnesia.
Physical properties about Ketamine are: (1)ACD/LogP: 3.012; (2)ACD/LogD (pH 5.5): 2.01; (3)ACD/LogD (pH 7.4): 2.97; (4)ACD/BCF (pH 5.5): 11.46; (5)ACD/BCF (pH 7.4): 102.86; (6)ACD/KOC (pH 5.5): 103.64; (7)ACD/KOC (pH 7.4): 930.33; (8)#H bond acceptors: 2; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 2; (11)Index of Refraction: 1.562; (12)Molar Refractivity: 65.724 cm3; (13)Molar Volume: 202.594 cm3; (14)Polarizability: 26.055 10-24cm3; (15)Surface Tension: 43.8880004882813 dyne/cm; (16)Density: 1.173 g/cm3; (17)Flash Point: 173.816 °C; (18)Enthalpy of Vaporization: 60.99 kJ/mol; (19)Boiling Point: 363.792 °C at 760 mmHg
You can still convert the following datas into molecular structure:
(1)InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3;
(2)InChIKey=YQEZLKZALYSWHR-UHFFFAOYSA-N;
(3)Smilesc1([C@@]2(C(CCCC2)=O)NC)c(cccc1)Cl
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 400mg/kg (400mg/kg) | British Journal of Anesthesia. Vol. 55, Pg. 457, 1983. | |
mouse | LD50 | intravenous | 77mg/kg (77mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC | Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 1, Pg. 119, 1975. |