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Basic information

  • Name:
  • L-Aspartic acid

  • CAS No.:
  • 56-84-8

  • Formula:
  • C4H7NO4
  • Synonyms:
  • L-Asparaginic acid;(2S)-2-aminobutanedioic acid;(S)-(+)-Aminosuccinic acid;L-(+)-Aspartic acid;(2S)-Aspartic acid;(+)-Aspartic acid;Aspartic acid, L- (8CI);(S)-Aminobutanedioic acid;L-Aspartate;(S)-Aspartic acid;Aspartic acid, L-;Butanedioic acid, amino-, (S)-;
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Chemistry

Structure of L-Aspartic acid (CAS NO.56-84-8):

IUPAC Name: (2S)-2-aminobutanedioic acid 
Empirical Formula: C4H7NO4
Molecular Weight: 133.1027 
EINECS: 200-291-6 
Index of Refraction: 1.531
Molar Refractivity: 27.2 cm3
Molar Volume: 87.8 cm3
Surface Tension: 78.2 dyne/cm
Density: 1.514 g/cm3
Flash Point: 113.5 °C
Enthalpy of Vaporization: 55.26 kJ/mol 
Melting Point: >300 °C (dec.)(lit.)
Boiling Point: 264.1 °C at 760 mmHg
Vapour Pressure: 0.00289 mmHg at 25°C 
Water Solubility: 5 g/L (25 ºC) 
Physical Appearance: White crystalline powder
Stability: Stable. Combustible. Incompatible with strong oxidising agents. 
Product Categories: Food & Feed ADDITIVES  ;  chiral ; Aspartic acid [Asp, D] ; Amino Acids and Derivatives ; alpha-Amino Acids ; Amino Acids ; Biochemistry ; for Resolution of Bases ; Optical Resolution ; Synthetic Organic Chemistry ; Nutritional Supplements ; L-Amino Acids ; Amino Acids ; Glutamate receptor ; aspartic acid ; amino acid ; bio-chemical ; chemicals ; food additive ; food additives ; food flavor ; organic acids ; pharmaceutical intermediate ; sweetener
Synonyms of L-Aspartic acid (CAS NO.56-84-8): (2S)-Aspartic acid ; (S)-Aminobutanedioic acid ; (S)-Aspartic acid ;
 Acide aspartique ; Acido aspartico ; Acidum asparticum ; Aminosuccinic acid ; Asparagic acid ; Asparaginic acid ;
 Asparaginsaeure ; Aspartate ; Aspartate, L- ; Aspartic acid ; Aspatofort ; L( )-Aminobernsteinsaeure ; L-2-Aminobutanedioic acid ; L-Aminosuccinic acid ; L-Asparaginsaeure ; L-Asparaginsyra ; L-Aspartinsaeure .

Uses

 L-Aspartic acid (CAS NO.56-84-8) is used for synthetic sweetener.
In medicine, it is used in the treatment of heart disease, and it also used as liver promoting agents, AMMONIA antidote, elimination fatigue,  amino acid composition infusion, ect.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 6gm/kg (6000mg/kg)   Pharmaceutical Chemistry Journal Vol. 25, Pg. 569, 1991.

Safety Profile

Hazard Codes: IrritantXi,HarmfulXn
Risk Statements: 36-36/37/38-20/21/22 
R36: Irritating to eyes. 
R36/37/38: Irritating to eyes, respiratory system and skin. 
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-24/25-22-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S24/25: Avoid contact with skin and eyes. 
S22: Do not breathe dust. 
S36: Wear suitable protective clothing.
WGK Germany: 2
RTECS: CI9098500
F: 10
HazardClass: IRRITANT
HS Code: 29224995

Specification

Personal Protection:
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. 

Fire Fighting: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

First Aid Measures:
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Storage: Store in a tightly closed container. Keep from contact with oxidizing materials. Keep away from direct light.
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

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