Table of contents:
IUPAC Name of L-Carnitine (CAS NO.541-15-1): (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate
Synonyms: 3-Hydroxy-4-(trimethylammonio)butanoate ; Vitamin BT
CAS number: 541-15-1
Molecular Formula: C7H15NO3
Molecular Weight: 161.199 g/mol
refractive index -32 ° (C=1, H2O)
alpha: -31 º (c=10, H2O)
Merck: 14,1849
BRN: 4292315
storage temp.: 2-8 °C
Melting point: 208-212 °C
Water Solubility of L-Carnitine (CAS NO.541-15-1): 2500 g/L (20 °C)
Appearance of L-Carnitine (CAS NO.541-15-1): White crystalline
L-Carnitine (CAS NO.541-15-1) was originally found as a growth factor for mealworms and labeled vitamin Bt.
The use of L-Carnitine (CAS NO.541-15-1) showed some promise in a controlled trial in selected cases of male infertility improving sperm quality.L-Carnitine improved glucose disposal among 15 patients with type II diabetes and 20 healthy volunteers.It is essential cofactor of fatty acid metabolism, and it is required for the transport of fatty acids through the inner mitochondrial membrane. It is synthetized primarily in the liver and kidney, and it highest concentrations found in heart and skeletal muscle.
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | unreported | 7gm/kg (7000mg/kg) | Cancer Treatment Reports. Vol. 63, Pg. 558, 1979. | |
| mouse | LD50 | intraperitoneal | 750mg/kg (750mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967. | |
| mouse | LD50 | subcutaneous | 9gm/kg (9000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS |
Acta Biologica et Medica Germanica. Vol. 35, Pg. 645, 1976. |
Hazard Codes:
Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 3
RTECS: BP2980000
F: 3-10
Hazard Note: Irritant
HS Code: 29239000
In animals, carnitine is biosynthesized primarily in the liver and kidneys from the amino acids lysine or methionine.Carnitine transports long-chain acyl groups from fatty acids into the mitochondrial matrix.L-Carnitine (CAS NO.541-15-1) products and supplements are not allowed to be imported into Canada (Health Canada).L-Carnitine (CAS NO.541-15-1) is stable under normal temperatures and pressures, and it absorbs moisture or water from the air. L-Carnitine (CAS NO.541-15-1) should avoid the condition like incompatible materials, exposure to moist air or water. It is incompatibilities with other materials strong oxidizing agents. Its hazardous decomposition products are carbon monoxide, oxides of nitrogen oxides, carbon monoxide, carbon dioxide.
