LookChem

L-carnitine (541-15-1)

Please post your buying leads,so that our qualified suppliers will soon contact you!
Required Fields
 Chemistry

IUPAC Name of L-Carnitine (CAS NO.541-15-1): (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate
Synonyms: 3-Hydroxy-4-(trimethylammonio)butanoate ; Vitamin BT
CAS number: 541-15-1
Molecular Formula: C7H15NO
Molecular Weight: 161.199 g/mol
refractive index -32 ° (C=1, H2O)
alpha: -31 º (c=10, H2O)
Merck: 14,1849
BRN: 4292315 
storage temp.: 2-8 °C
Melting point: 208-212 °C
Water Solubility of L-Carnitine (CAS NO.541-15-1): 2500 g/L (20 °C) 
Appearance of L-Carnitine (CAS NO.541-15-1): White crystalline

 History

L-Carnitine (CAS NO.541-15-1) was originally found as a growth factor for mealworms and labeled vitamin Bt.
 

 Uses

The use of L-Carnitine (CAS NO.541-15-1) showed some promise in a controlled trial in selected cases of male infertility improving sperm quality.L-Carnitine improved glucose disposal among 15 patients with type II diabetes and 20 healthy volunteers.It is essential cofactor of fatty acid metabolism, and it is required for the transport of fatty acids through the inner mitochondrial membrane. It is synthetized primarily in the liver and kidney, and it highest concentrations found in heart and skeletal muscle.

 Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 unreported 7gm/kg (7000mg/kg)   Cancer Treatment Reports. Vol. 63, Pg. 558, 1979.
mouse LD50 intraperitoneal 750mg/kg (750mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.
mouse LD50 subcutaneous 9gm/kg (9000mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Acta Biologica et Medica Germanica. Vol. 35, Pg. 645, 1976.
 

 L-Carnitine (CAS NO.541-15-1) hasn't been listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.

 Safety Profile

Hazard Codes:IrritantXi
Risk Statements: 36/37/38 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-37/39 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing. 
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 3
RTECS: BP2980000
F: 3-10
Hazard Note: Irritant
HS Code: 29239000
 

 Specification

In animals, carnitine is biosynthesized primarily in the liver and kidneys from the amino acids lysine or methionine.Carnitine transports long-chain acyl groups from fatty acids into the mitochondrial matrix.L-Carnitine (CAS NO.541-15-1) products and supplements are not allowed to be imported into Canada (Health Canada).L-Carnitine (CAS NO.541-15-1) is stable under normal temperatures and pressures, and it absorbs moisture or water from the air. L-Carnitine (CAS NO.541-15-1) should avoid the condition like incompatible materials, exposure to moist air or water. It is incompatibilities with other materials strong oxidizing agents. Its hazardous decomposition products are carbon monoxide, oxides of nitrogen oxides, carbon monoxide, carbon dioxide. 

  • L-carnitine Basic information

  • Product Name:L-carnitine
  • CAS No:541-15-1
  • Formula:C7H15NO3
  • Molecular Structure of (<span class=bigs><a href=/cas-541/541-15-1.html />541-15-1</a></span>) (L(-)-Carnitine)