Basic information
- Name:
Levobunolol hydrochloride
- CAS No.:
27912-14-7
- Molecular Structure:
- Formula:
- C17H25NO3.HCl
- Molecular Weight:
- 327.89
- Synonyms:
- (-)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalene-1(2H)-one hydrochloride;Vistagan;(2S)-N-(tert-butyl)-2-hydroxy-3-[(5-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]propan-1-aminium chloride;Betagan (TN);Prestwick_167;Levobunolol hydrochloride (JAN/USP);1(2H)-Naphthalenone,5-[(2S)-3-[(1,1- dimethylethyl)amino]-2-hydroxypropoxy]-3,4- dihydro-,hydrochloride;Levobunolol hydrochloride [USAN];(-)-3,4-Dihydro-5-(3-(tert-butylamino)-2-hydroxypropoxy)-1(2H)-naphthalenone hydrochloride;1(2H)-Naphthalenone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-, hydrochloride, (-)-;Betagan;
- EINECS:
- 248-725-3
- Boiling Point:
- 464.4 °C at 760 mmHg
- Flash Point:
- 234.7 °C
Famous Chemical Enterprises
-
Livzon -
Total -
Shell -
Dupont -
Exxonmobil -
Akzonobel -
Basf -
Bayer -
BP
Please post your buying leads,so that our qualified suppliers will soon
contact you!
*Required Fields
Chemistry
Product Name: Levobunolol hydrochloride (CAS NO.27912-14-7)
Molecular Formula: C17H26ClNO3
Molecular Weight: 327.85g/mol
Mol File: 27912-14-7.mol
Einecs: 248-725-3
Appearance: Glaucoma drug
Boiling point: 464.4 °C at 760 mmHg
Flash Point: 234.7 °C
Enthalpy of Vaporization: 76.47 kJ/mol
Vapour Pressure: 2.01E-09 mmHg at 25°C
H-Bond Donor: 3
H-Bond Acceptor: 4
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | oral | 100mg/kg (100mg/kg) | General Pharmacology. Vol. 17, Pg. 373, 1986. | |
| hamster | LD50 | oral | 435mg/kg (435mg/kg) | General Pharmacology. Vol. 17, Pg. 373, 1986. | |
| man | TDLo | ocular | 8571nL/kg/9W- (8571mL/kg) | BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" CARDIAC: PULSE RATE | American Heart Journal. Vol. 127, Pg. 689, 1994. |
| mouse | LD50 | intravenous | 78mg/kg (78mg/kg) | General Pharmacology. Vol. 17, Pg. 373, 1986. | |
| mouse | LD50 | oral | 1220mg/kg (1220mg/kg) | "Pharmacology of Antihypertensive Drugs," Scriabine, A., ed., New York, Raven Press, 1980Vol. -, Pg. 317, 1980. | |
| rat | LD50 | intravenous | 25mg/kg (25mg/kg) | General Pharmacology. Vol. 17, Pg. 373, 1986. | |
| rat | LD50 | oral | 700mg/kg (700mg/kg) | General Pharmacology. Vol. 17, Pg. 373, 1986. | |
| women | TDLo | ocular | 1uL/kg/12H-I (0.001mL/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTION | Medical Journal of Australia. Vol. 161, Pg. 576, 1994. |
Safety Profile
A poison by ingestion and intravenous routes. Questionable carcinogen with experimental neoplastigenic data reported. When heated to decomposition it emits toxic vapors of NOx and HCl.
Specification
Levobunolol hydrochloride ,its CAS NO. is 27912-14-7,the synonyms is (-)-3,4-Dihydro-5-(3-(tert-butylamino)-2-hydroxypropoxy)-1(2h)-naphthalenone ; (-)-Rochlorid;3,4-dihydro-5-(3-(tert-butylamino)-2-hydroxypropoxy)-1(2h)-naphthalenonhyd ; Betagan;gotensin ; l-Bunololhydrochloride ; Vistagan ; W7000a .