Lithium bromide

Lithium bromide(7550-35-8) was used as a sedative beginning in the early 1900s, but it fell into disfavor in the 1940s when some heart patients died after using it as a salt substitute. Like lithium carbonate and lithium chloride it was used as treatment for bipolar disorder.

Reported in EPA TSCA Inventory.

The IUPAC name of this chemical is lithium bromide. With the CAS registry number 7550-35-8, it is also named as Lithium monobromide. The product's categories are Inorganics; Crystal Grade Inorganics; Lithium Salts; Lithium Metal and Ceramic Science; Analytical Reagents for General Use; Inorganic Salts; Synthetic Reagents; Essential Chemicals; Reagent Plus; Routine Reagents. It is white powder which is easily soluble in water, slightly soluble in pyridine, in methanol, soluble in alcohol, ether acetone, ethylene glycol and other organic solvents. What's more, it is stable. And the anhydrous form is extremely hygroscopic. Additioanlly, this chemical should be sealed in the container and stored in the ventilate and dry place.

The other characteristics of this product can be summarized as: (1)H-Bond Donor: 0; (2)H-Bond Acceptor: 1; (3)Rotatable Bond Count: 0; (4)Exact Mass: 85.934342; (5)MonoIsotopic Mass: 85.934342; (6)Topological Polar Surface Area: 0; (7)Heavy Atom Count: 2; (8)Formal Charge: 0; (9)Complexity: 2; (10)Isotope Atom Count: 0; (11)Covalently-Bonded Unit Count: 2; (12)Density: 3.464 g/cm³; (13)Melting point: 550 °C; (14)Boiling point: 1265 °C.

Preparation of Lithium bromide: It can be obtained by the neutralization reaction of lithium hydroxide and hydrobromic acid. By bleaching, filtration, concentration filtrate, filtration, concentration and crystallization, separation, we can get the product. LiOH+HBr→LiBr+H₂O

Uses of Lithium bromide: It is used in air-conditioning systems as desiccant. Otherwise the salt is useful as a reagent in organic synthesis. It is also used in pharmaceutical industry and photographic industry. And it was used as a sedative beginning in the early 1900s, but it fell into disfavor in the 1940s when some heart patients died after using it as a salt substitute.

When you are using this chemical, please be cautious about it as the following:
It is extremely flammable. And it is not only harmful if swallowed, but also irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

People can use the following data to convert to the molecule structure.
1. SMILES:[Li+].[Br-]
2. InChI:InChI=1/BrH.Li/h1H;/q;+1/p-1 
3. InChIKey:AMXOYNBUYSYVKV-REWHXWOFAS

The following are the toxicity data which has been tested.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	intraperitoneal	580mg/kg (580mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 33(10), Pg. 57, 1989.
mouse	LD50	intraperitoneal	1160mg/kg (1160mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 33(10), Pg. 57, 1989.
mouse	LD50	oral	1840mg/kg (1840mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 33(10), Pg. 57, 1989.
mouse	LD50	subcutaneous	1680mg/kg (1680mg/kg)		Russian Pharmacology and Toxicology Vol. 33, Pg. 266, 1970.
rat	LD50	oral	1800mg/kg (1800mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 33(10), Pg. 57, 1989.