Basic information
- Name:
Licorice extract
- CAS No.:
68916-91-6
- Deleted CAS:
- 8008-94-4, 8057-63-4, 85085-44-5
- Synonyms:
- Licorice,ext.;Glycyrrhiza extract;Kanzou;Lacrinat;Licorice (pharmaceutical);Natural products,pharmaceutical, licorice;Licorice root extract;Liquoriceroot ext.;
- EINECS:
- 272-837-1
- Solubility:
- Soluble in water and ethanol
- Appearance:
- Brown or red brown liquid, taste sweet, slightly bitter
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Specification
The Licorice extract, with the CAS registry number 68916-91-6, is also known as Glycyrrhiza extract. It belongs to the product categories of Natural Plant Extract; Nutraceuticals. Its EINECS number is 272-837-1. Its classification codes are: (1)Drug / Therapeutic Agent; (2)Mutation data; (3)Natural Product. It is used as edible spices, sweetener, sauce and surfactant. This chemical can be prepared by smashing the root and rhizome of Glycyrrhizauralensis and G.glabra.
The toxicity data is as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| man | TDLo | oral | 209gm/kg/2Y-I (209000mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: MUSCLE WEAKNESS CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE | Italian Journal of Neurological Sciences. Vol. 4, Pg. 493, 1983. |
| mouse | LD50 | intraperitoneal | 1500mg/kg (1500mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BLOOD: CHANGES IN SPLEEN | Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977. |
| mouse | LD50 | oral | > 7500mg/kg (7500mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977. | |
| mouse | LD50 | subcutaneous | 4gm/kg (4000mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BLOOD: CHANGES IN SPLEEN | Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977. |
| rat | LD50 | intraperitoneal | 1420mg/kg (1420mg/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977. |
| rat | LD50 | oral | 14200mg/kg (14200mg/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977. |
| rat | LD50 | subcutaneous | 4200mg/kg (4200mg/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977. |