Basic information
- Name:
Lornoxicam
- CAS No.:
70374-39-9
- Molecular Structure:
- Formula:
- C13H10ClN3O4S2
- Molecular Weight:
- 371.82
- Synonyms:
- Chlortenoxicam;Lornoxicamum;6-Chloro-4-hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide;2H-Thieno(2,3-e)-1,2-thiazine-3-carboxamide, 6-chloro-4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide;
- Density:
- 1.742 g/cm3
- Melting Point:
- 225-230 °C (dec.)
- Appearance:
- Crystalline solid
- Hazard Symbols:
Xi- Risk Codes:
- 36/37/38
- Safety Description:
- 26-36 Details
Famous Chemical Enterprises
-
Livzon -
Total -
Shell -
Dupont -
Exxonmobil -
Akzonobel -
Basf -
Bayer -
BP
Please post your buying leads,so that our qualified suppliers will soon
contact you!
*Required Fields
Chemistry
Molecular structure of Lornoxicam (CAS NO.70374-39-9) is:
Product Name: Lornoxicam
CAS Registry Number: 70374-39-9
IUPAC Name: (3E)-6-chloro-3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxothieno[2,3-e]thiazin-4-one
Molecular Weight: 371.8192 [g/mol]
Molecular Formula: C13H10ClN3O4S2
XLogP3-AA: 3.1
H-Bond Donor: 2
H-Bond Acceptor: 7
Melting Point: 225-230°C (dec.)
Surface Tension: 91.82 dyne/cm
Density: 1.742 g/cm3
Product Categories: APIs;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Fused Ring Systems
History
Lornoxicam is found in the plasma in unchanged form and as its hydroxylated metabolite.
Uses
Lornoxicam (CAS NO.70374-39-9) is a non-steroidal anti-inflammatory drug of the oxicam class,with analgesic ,anti-inflammatory and antipyretic propertiesis .It is used for inflammatory disease of the joints ,osteoarthritis,pain following surgery as well as pain in the lower back and hip which travels down the back of the thigh into the leg .
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | oral | 5730ug/kg (5.73mg/kg) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 94, Pg. 61, 1989. |
Safety Profile
Hazard Codes: 
Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
Specification
Lornoxicam , its cas register number is 70374-39-9. It also can be called 6-Chloro-4-hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide ; 2H-Thieno(2,3-e)-1,2-thiazine-3-carboxamide, 6-chloro-4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide ; Chlortenoxicam ; Lornoxicamum .It is a crystalline solid and available in oral and parenteral formulations. It is absorbed rapidly and almost completely from the gastro-intestinal tract.