Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Maraviroc

Related Products

Hot Products

Name

Maraviroc

EINECS 609-456-0
CAS No. 376348-65-1 Density 1.29 g/cm3
PSA 63.05000 LogP 6.27970
Solubility N/A Melting Point 79-81 °C
Formula C29H41F2N5O Boiling Point N/A
Molecular Weight 513.674 Flash Point N/A
Transport Information N/A Appearance Brown solid
Safety 22-36 Risk Codes 48/22
Molecular Structure Molecular Structure of 376348-65-1 (Maraviroc) Hazard Symbols Xn
Synonyms

Cyclohexanecarboxamide,4,4-difluoro-N-[(1S)-3-[(3-exo)-3-[3-methyl-5-(1-methylethyl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl]-;Celsentri;UK 427857;

Article Data 12

Maraviroc Specification

Maraviroc is one kind of brown solid. Its chemical name is 4,4-Difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide. Besides, Maraviroc belongs to Anti-AIDS; Chiral Reagents; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals. In addition, Maraviroc can soluble to 75 mM in DMSO and to 100 mM in ethanol.

Physical properties about Maraviroc are: (1)ACD/LogP: 5.304; (2)# of Rule of 5 Violations: 2; (3)ACD/LogD (pH 5.5): 2.21; (4)ACD/LogD (pH 7.4): 2.78; (5)ACD/BCF (pH 5.5): 5.14; (6)ACD/BCF (pH 7.4): 18.76; (7)ACD/KOC (pH 5.5): 14.86; (8)ACD/KOC (pH 7.4): 54.28; (9)#H bond acceptors: 6; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 8; (12)Index of Refraction: 1.628; (13)Molar Refractivity: 141.101 cm3; (14)Molar Volume: 397.785 cm3; (15)Polarizability: 55.937 10-24cm3; (16)Surface Tension: 44.2509994506836 dyne/cm; (17)Density: 1.291 g/cm3;

Uses of Maraviroc: Maraviroc (CAS NO.376348-65-1) has been used for non-competitive CCR5 receptor antagonist as a potent antiviral durg inhibiting binding of HIV viral coat protein gp120. Besides, it is a antiviral. It also appeared to reduce graft-versus-host disease in patients treated with allogeneic bone marrow transplantation for leukemia. In addition, Maraviroc can be made into the tablet. And Maraviroc comes as a tablet to take by mouth. It is usually taken with or without food two times a day.

You can still convert the following datas into molecular structure:
(1)InChI=1S/C29H41F2N5O/c1-19(2)27-34-33-20(3)36(27)25-17-23-9-10-24(18-25)35(23)16-13-26(21-7-5-4-6-8-21)32-28(37)22-11-14-29(30,31)15-12-22/h4-8,19,22-26H,9-18H2,1-3H3,(H,32,37)/t23-,24+,25-,26-/m0/s1;
(2)InChIKey=GSNHKUDZZFZSJB-QYOOZWMWSA-N;
(3)SmilesC1[C@H]2N([C@@H](C[C@H]1n1c(nnc1C(C)C)C)CC2)CC[C@@H](c1ccccc1)NC(C1CCC(CC1)(F)F)=O

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 376348-65-1