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Mepitiostane

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Name

Mepitiostane

EINECS N/A
CAS No. 21362-69-6 Density 1.13g/cm3
PSA 43.76000 LogP 6.42490
Solubility N/A Melting Point 98-101°
Formula C25H40 O2 S Boiling Point 485.2°Cat760mmHg
Molecular Weight 404.71 Flash Point 247.2°C
Transport Information N/A Appearance N/A
Safety Human systemic effects by ingestion: dermatitis, liver changes, and transaminase activity. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx. Risk Codes N/A
Molecular Structure Molecular Structure of 21362-69-6 (Mepitiostane) Hazard Symbols N/A
Synonyms

Cyclopentanone,2a,3a-epithio-5a-androstan-17b-yl methyl acetal (8CI); 2,3-Epithio-1H-cyclopenta[a]phenanthrene,androstane deriv.; 5a-Androstane, 2a,3a-epithio-17b-[(1-methoxycyclopentyl)oxy]-(8CI); 10364S; 2a,3a-Epithio-17b-(1-methoxycyclopentyloxy)-5a-androstane; 2a,3a-Epithio-17b-(cyclopentylmethoxy)-5a-androstane; 2a,3a-Epithio-5a-androstan-17b-yl 1-methoxycyclopentyl ether;Mepitiostane

 

Mepitiostane Chemical Properties

Systematic Name: (2alpha,3alpha,5alpha,17beta)-17-[(1-methoxycyclopentyl)oxy]-2,3-epithioandrostane
Synonyms of Mepitiostane (CAS NO.21362-69-6): 2-alpha,3-alpha-Epithio-17-beta-yl 1-methoxycyclopentyl ether ; Androstane, 2,3-epithio-17-((1-methoxycyclopentyl)oxy)-, (2-alpha,3-alpha,5-alpha,17-beta) ; Cyclopentanone, 2-alpha, 3-alpha-epithio-5-alpha-androstan-17-beta-yl methyl acetal ; Mepitiostano ; Mepitiostanum ; 5-alpha-Androstane, 2-alpha,3-alpha-epithio-17-beta-(1-methoxycyclopentyloxy)-
CAS NO: 21362-69-6
Molecular Formula: C25H40O2S
Molecular Weight : 404.6489
Molecular Structure:
H bond acceptors: 2
H bond donors: 0
Freely Rotating Bonds: 3
Polar Surface Area: 43.76 Å2
Index of Refraction: 1.568
Molar Refractivity: 116.921 cm3
Molar Volume: 357.305 cm3
Surface Tension: 44.397 dyne/cm
Density: 1.133 g/cm3
Flash Point: 247.247 °C
Enthalpy of Vaporization: 72.209 kJ/mol
Boiling Point: 485.211 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C

Mepitiostane Uses

 Mepitiostane (CAS NO.21362-69-6) is an anabolic steroid,which is purported to also have anti-estrogen properties.

Mepitiostane Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo oral 400ug/kg (0.4mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Cancer Vol. 41, Pg. 758, 1978.
mouse LD intraperitoneal > 6130mg/kg (6130mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 779, 1978.
mouse LD oral > 6130mg/kg (6130mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 779, 1978.
mouse LD subcutaneous > 6130mg/kg (6130mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 779, 1978.
rat LD intraperitoneal > 5gm/kg (5000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 779, 1978.
rat LD oral > 5gm/kg (5000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 779, 1978.
rat LD subcutaneous > 5gm/kg (5000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 779, 1978.

Mepitiostane Safety Profile

Human systemic effects by ingestion: dermatitis, liver changes, and transaminase activity. Experimental reproductive effects. When Mepitiostane (CAS NO.21362-69-6) is heated to decomposition, it emits toxic fumes of SOx.

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