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Mestanolone

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Name

Mestanolone

EINECS 208-302-6
CAS No. 521-11-9 Density 1.064 g/cm3
PSA 37.30000 LogP 4.34920
Solubility practically insoluble < RESIDUES 0.25% max Melting Point 191 °C
Formula C20H32O2 Boiling Point 416.1 °C at 760mmHg
Molecular Weight 304.473 Flash Point 177.6 °C
Transport Information N/A Appearance White Solid
Safety 22-36 Risk Codes 40
Molecular Structure Molecular Structure of 521-11-9 (Mestanolone) Hazard Symbols HarmfulXn
Synonyms

5a-Androstan-3-one, 17b-hydroxy-17-methyl-(6CI,7CI,8CI);17a-Methyl-17b-hydroxy-5a-androstan-3-one;17a-Methyl-5a-androstan-17b-ol-3-one;17a-Methyl-5a-dihydrotestosterone;17a-Methylandrostan-17b-ol-3-one;17a-Methylandrostan-3-on-17b-ol;17a-Methylandrostanolone;17a-Methyldihydrotestosterone;17b-Hydroxy-17-methyl-5a-androstan-3-one;17b-Hydroxy-17a-methyl-3-androstanone;17b-Hydroxy-17a-methyl-5a-androstan-3-one;5a-Androstan-17a-methyl-17b-ol-3-one;Androstalone;Assimil;Mestalone;Mestanolon;Mestanolone;Methybol;Methylandrostanolone;Methylantalon;NSC 18219;Preroide;RU 143;Tantarone;

Article Data 25

Mestanolone Specification

 The Mestanolone with the cas number 521-11-9, is also called (1) 17-alpha-Methyldihydrotestosterone ; (2) 17alpha-Methyl-5alpha-dihydrotestosterone ; (3) 17alpha-Methylandrostan-17beta-ol-3-one ; (4) 17alpha-Methylandrostanolone ; (5) 17alpha-Methyldihydrotestosterone ; (6) 17alpha-methyl-5alpha-androstan-17beta-ol-3-one ; (7) 17alpha-methylandrostan-3-on-17beta-ol ; (8) 17beta-Hydroxy-17alpha-methyl-5alpha-androstan-3-one ; (9) 5-alpha-Androstane-17-alpha-methyl-17-beta-ol-3-one ; (10) 5alpha-Androstane-17alpha-methyl-17beta-ol-3-one ; (11) Andoron ; (12) Androstalone ; (13) Assimil ; (14) Ermalone (VAN) ; (15) Mestanolona ; (16) Mestanolone ; (17) Mestanolonum ; (18) Methybol ; (19) Methylantalon ; (20) Methyldihydrotestosterone ; (21) Preroide ; (22) Tantarone . It belongs to the following product Categories: (1)Steroids; (2)Biochemistry; (3)Hydroxyketosteroids 

Propertes of Mestanolone: (1)ACD/LogP: 4.29 ; (2)# of Rule of 5 Violations: 0 ; (3)ACD/LogD (pH 5.5): 4.29 ; (4)ACD/LogD (pH 7.4): 4.29 ; (5)ACD/BCF (pH 5.5): 1076.26 ; (6)ACD/BCF (pH 7.4): 1076.26 ; (7)ACD/KOC (pH 5.5): 5150.44 ; (8)ACD/KOC (pH 7.4): 5150.44 ; (9)#H bond acceptors: 2 ; (10)#H bond donors: 1 ; (11)#Freely Rotating Bonds: 1 ; (12)Polar Surface Area: 26.3 Å2 ; (13)Index of Refraction: 1.528 ; (14) Molar Refractivity: 88.1 cm3 ; (15)Molar Volume: 286 cm3 ; (16)Polarizability: 34.92 ×10-24cm3 ; (17)Surface Tension: 39.2 dyne/cm ; (18)Density: 1.064 g/cm3 ; (19)Flash Point: 177.6 °C ; (20)Enthalpy of Vaporization: 77.31 kJ/mol ; (21)Boiling Point: 416.1 °C at 760 mmHg ; (22)Vapour Pressure: 1.16E-08 mmHg at 25°C

The Mestanolone is an orally bioavailable androgenic steroid that is highly androgenic while only slightly anabolic. It is incapable of aromatization and is not an agonist of the progesterone receptor. Dosages range from 10mg to 30mg a day for males. Women should avoid Mestanolone for it is very androgenic. Long term use, more than 12 weeks should be avoided do to hepatoxicity. Since Mestanolone is unable to convert to estrogen, it is very useful during cutting phase's or when one wishes to avoid excess weight gain.

You can still convert the following datas into molecular structure :
1. SMILES: O=C2C[C@@H]1CC[C@@H]3[C@@H]([C@@]1(C)CC2)CC[C@]4([C@H]3CC[C@@]4(O)C)C
2. InChI: InChI=1/C20H32O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h13,15-17,22H,4-12H2,1-3H3/t13-,15+,16-,17-,18-,19-,20-/m0/s1

The Mestanolone toxic data can be showed in the following sheet.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1240mg/kg (1240mg/kg)   Drugs in Japan Vol. 6, Pg. 817, 1982.
mouse LD50 oral > 3gm/kg (3000mg/kg)   Drugs in Japan Vol. 6, Pg. 817, 1982.
mouse LD50 subcutaneous > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 817, 1982.
rat LD50 intraperitoneal > 2gm/kg (2000mg/kg)   Drugs in Japan Vol. 6, Pg. 817, 1982.
rat LD50 oral > 3gm/kg (3000mg/kg)   Drugs in Japan Vol. 6, Pg. 817, 1982.
rat LD50 subcutaneous > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 817, 1982.