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Molecular structure of Metalol hydrochloride (CAS NO.955-48-6) is:
Product Name: Metalol hydrochloride
CAS Registry Number: 955-48-6
IUPAC Name: N-[4-[1-hydroxy-2-(methylamino)propyl]phenyl]methanesulfonamide hydrochloride
Molecular Weight: 294.79816 [g/mol]
Molecular Formula: C11H19ClN2O3S
H-Bond Donor: 4
H-Bond Acceptor: 5
Flash Point: 215.7 °C
Enthalpy of Vaporization: 72.63 kJ/mol
Boiling Point: 433.1 °C at 760 mmHg
Vapour Pressure: 2.86E-08 mmHg at 25°C
Classification Code: Anti-adrenergic [beta-receptor]
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | intraperitoneal | 485mg/kg (485mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA | Journal of Pharmacology and Experimental Therapeutics. Vol. 149, Pg. 161, 1965. |
mouse | LD50 | intraperitoneal | 785mg/kg (785mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA | Journal of Pharmacology and Experimental Therapeutics. Vol. 149, Pg. 161, 1965. |
mouse | LD50 | oral | > 6gm/kg (6000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ATAXIA BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 149, Pg. 161, 1965. |
rabbit | LD50 | oral | 1250mg/kg (1250mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA | Journal of Pharmacology and Experimental Therapeutics. Vol. 149, Pg. 161, 1965. |
rat | LD50 | intraperitoneal | 850mg/kg (850mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA | Journal of Pharmacology and Experimental Therapeutics. Vol. 149, Pg. 161, 1965. |
rat | LD50 | oral | > 6gm/kg (6000mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Journal of Pharmacology and Experimental Therapeutics. Vol. 149, Pg. 161, 1965. |
Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl. See also SULFONATES.
Metalol hydrochloride , its cas register number is 955-48-6. It also can be called 4'-(1-Hydroxy-2-(methylamino)propyl methanesulfonanilide monohydrochloride ; MJ 1998 ; Metalol HCl ; Metalol hydrochloride ; Methanesulfonamide, N-(4-(1-hydroxy-2-(methylamino)propyl)phenyl)-, monohydrochloride ; Methanesulfonamide, N-(4-(1-hydroxy-2-(methylamino)propyl)phenyl)-, monohydrochloride ; Methanesulfonanilide, 4'-(1-hydroxy-2-(methylamino)propyl)-, hydrochloride .