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Methyl-5-norbornene-2,3-dicarboxylic anhydride

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Name

Methyl-5-norbornene-2,3-dicarboxylic anhydride

EINECS 246-644-8
CAS No. 25134-21-8 Density 1.302 g/cm3
PSA 43.37000 LogP 0.89820
Solubility reacts with water Melting Point N/A
Formula C10H10O3 Boiling Point 326.1 °C at 760 mmHg
Molecular Weight 178.20 Flash Point 157.1 °C
Transport Information UN 3265 8/PG 2 Appearance clear light yellow oily liquid
Safety 39-45-36/37/39-26 Risk Codes 22-36/37/38-42-34
Molecular Structure Molecular Structure of 25134-21-8 (Methyl-5-norbornene-2,3-dicarboxylic anhydride) Hazard Symbols HarmfulXn, CorrosiveC
Synonyms

4,7-Methanoisobenzofuran-1,3-dione,3a,4,7,7a-tetrahydromethyl-, (3aa,4a,7a,7aa)-;5-Norbornene-2,3-dicarboxylic anhydride, methyl- (6CI,7CI,8CI);3,6-Endomethylene-1,2,3,6-tetrahydro-3(or 4)-methylphthalic anhydride;AralditeHY 906;Ciba-Geigy 906;Epicure NMA;HY 906;Kayahard MCD;Lindride25;MEA 610;Methyl-endo-bicyclo[2.2.1]-5-heptene-2,3-dicarboxylic anhydride;Methylbicyclo[2.2.1]heptene-2,3-dicarboxylic anhydride;Methylendic anhydride;Methylnadic acid anhydride;Methyl nadic anhydride;Nadic methyl anhydride;endo-Methylenemethyltetrahydrophthalic anhydride;

 

Methyl-5-norbornene-2,3-dicarboxylic anhydride Consensus Reports

Reported in EPA TSCA Inventory.

Methyl-5-norbornene-2,3-dicarboxylic anhydride Specification

The systematic name of Methyl nadic anhydride is (3aR,4S,7aS)-8-methyl-3a,4,7,7a-tetrahydro-4,7-methano-2-benzofuran-1,3-dione. With the CAS registry number 25134-21-8, it is also named as 4,7-Methanoisobenzofuran-1,3-dione, 3a,4,7,7a-tetrahydromethyl-. The product's categories are norbornene derivatives and organics. It is clear light yellow oily liquid which is sensitive to moisture. It can be used as epoxy resin curing agent.

The Methyl nadic anhydride is harmful if swallowed. It is irritating to eyes, respiratory system and skin. And it also can cause burns. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

The other characteristics of this product can be summarized as: (1)ACD/LogP: 0.45; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.45; (4)ACD/LogD (pH 7.4): 0.45; (5)ACD/BCF (pH 5.5): 1.29; (6)ACD/BCF (pH 7.4): 1.29; (7)ACD/KOC (pH 5.5): 41.75; (8)#H bond acceptors: 3; (9)#H bond donors: 0; (10)Index of Refraction: 1.553; (11)Molar Refractivity: 43.78 cm3; (12)Molar Volume: 136.7 cm3; (13)Polarizability: 17.35×10-24 cm3; (14)Surface Tension: 42.9 dyne/cm; (15)Enthalpy of Vaporization: 56.83 kJ/mol; (16)Boiling Point: 326.1 °C at 760 mmHg; (17)Vapour Pressure: 0.00022 mmHg at 25°C; (18)Exact Mass: 178.062994; (19)MonoIsotopic Mass: 178.062994; (20)Topological Polar Surface Area: 43.4; (21)Heavy Atom Count: 13.

People can use the following data to convert to the molecule structure. 
1.SMILES: O=C1OC(=O)[C@@H]3[C@H]1[C@H]2/C=C\[C@H]3[C@H]2C;
2.InChI: InChI=1/C10H10O3/c1-4-5-2-3-6(4)8-7(5)9(11)13-10(8)12/h2-8H,1H3/t4-,5-,6-,7+,8-/m0/s1; 
3.InChIKey: SBKPSHZVULRXED-ZXVYDBTHBA.

The following is the toxicity data which has been tested.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 100mg/kg (100mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
National Technical Information Service. Vol. AD441-640,
rat LCLo inhalation 750mg/m3/4H (750mg/m3)   United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-0282-0431,
rat LD50 oral 914mg/kg (914mg/kg)   United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-0282-0431,
rat LD50 skin 4920mg/kg (4920mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: STIFFNESS

GASTROINTESTINAL: ALTERATION IN GASTRIC SECRETION
National Technical Information Service. Vol. OTS0555136,

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