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Methylergonovine maleate salt

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Name

Methylergonovine maleate salt

EINECS 260-734-4
CAS No. 57432-61-8 Density g/cm3
PSA 142.96000 LogP 1.96530
Solubility N/A Melting Point 1720C (dec)
Formula C20H25N3O2.C4H4O4 Boiling Point 638.4°Cat760mmHg
Molecular Weight 455.511 Flash Point 339.9°C
Transport Information UN 1544 Appearance N/A
Safety Poison by ingestion, intravenous, and intraperitoneal routes. Human teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. Risk Codes R23/24/25;R62   
Molecular Structure Molecular Structure of 57432-61-8 (Methylergonovine maleate salt) Hazard Symbols
Synonyms

Methergine;Ergoline-8-carboxamide,9,10-didehydro-N- [(1S)-1-(hydroxymethyl)propyl]-6-methyl-,(8a)-,(2Z)-2-butenedioate (1:1) (salt);Methylergometrine maleate (JP14);Methylergometrine maleate;Methylergonovine maleate;Methylergonovine maleate (USP);Methergine (TN);Erezin;METHYL ERGOMETRINE MALEATE;METHYLERGONOVINE MALEATE;METHYLERGOBASINE MALEATE;USAF UCTL-8;METHEGRIN;MALEIC ACID, METHYL ERGONOVINE;

 

Methylergonovine maleate salt Chemical Properties

Product Name: Methylergonovine maleate (CAS NO.57432-61-8)


Molecular Formula: C24H29N3O6
Molecular Weight: 455.5g/mol
Mol File: 57432-61-8.mol
Einecs: 260-734-4
Appearance: Crystalline Solid
Boiling point: 638.4 °C at 760 mmHg
Flash Point: 339.9 °C
Water Solubility: H2O: 25 mg/mL
Enthalpy of Vaporization: 99.09 kJ/mol
Vapour Pressure: 3.6E-17 mmHg at 25°C
XLogP3-AA:
H-Bond Donor: 5
H-Bond Acceptor: 7
Product Categories: Intermediates and Fine Chemicals; Metabolites and Impurities; Pharmaceuticals

Methylergonovine maleate salt Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 6mg/kg (6mg/kg)   National Technical Information Service. Vol. AD277-689,
mouse LD50 intravenous 85mg/kg (85mg/kg)   Drugs in Japan Vol. 6, Pg. 828, 1982.
mouse LD50 oral 187mg/kg (187mg/kg)   Drugs in Japan Vol. 6, Pg. 828, 1982.
rabbit LD50 intravenous 2600ug/kg (2.6mg/kg)   Drugs in Japan Vol. 6, Pg. 828, 1982.
rat LD50 intravenous 23mg/kg (23mg/kg)   Drugs in Japan Vol. 6, Pg. 828, 1982.
rat LD50 oral 93mg/kg (93mg/kg)   Drugs in Japan Vol. 6, Pg. 828, 1982.
women TDLo oral 36ug/kg/3D-I (0.036mg/kg) CARDIAC: CARDIOMYOPATHY INCLUDING INFARCTION

CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE
American Journal of Emergency Medicine. Vol. 16, Pg. 502, 1998.

Methylergonovine maleate salt Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Human teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Safety Information of Methylergonovine maleate (CAS NO.57432-61-8):
Hazard Codes: T
Risk Statements: 23/24/25-62 
23:  Toxic by inhalation 
24:  Toxic in contact with skin 
25:  Toxic if swallowed 
62:  Possible risk of impaired fertility
Safety Statements: 36/37/39-45
36:  Wear suitable protective clothing  
37:  Wear suitable gloves
39:  Wear eye/face protection 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

Methylergonovine maleate salt Specification

 Methylergonovine maleate ,its CAS NO. is 57432-61-8,the synonyms is Erezingen ; Maleicacid,methylergonovine ; Methergine ; Methylergobasinemaleate ; Methyl-ergonovinmaleate(1:1) ; Methylergometrine maleate ; Methylergonovine maleate salt .

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