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Mikamycin B

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Name

Mikamycin B

EINECS N/A
CAS No. 3131-03-1 Density 1.38g/cm3
PSA 227.96000 LogP 2.13220
Solubility N/A Melting Point 198°
Formula C45H54 N8 O10 Boiling Point 1202.1°Cat760mmHg
Molecular Weight 866.971 Flash Point 680.8°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 3131-03-1 (mikamycin B) Hazard Symbols N/A
Synonyms

OstreogrycinB (6CI,7CI); Virginiamycin S1, 4-[4-(dimethylamino)-N-methyl-L-phenylalanine]-;12H-Pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecine,cyclic peptide deriv.; Antibiotic PA 114B; Antibiotic PA 114B1; Glycine,N-[(3-hydroxy-2-pyridinyl)carbonyl]-L-threonyl-D-2-aminobutanoyl-L-prolyl-4-(dimethylamino)-N-methyl-L-phenylalanyl-4-oxo-L-2-piperidinecarbonyl-L-2-phenyl-,r-lactone; Mikamycin B; MikamycinIA; NSC 92554; PA 114B; Pristinamycin P 1; Streptogramin B; Vernamycin Ba

 

Mikamycin B Chemical Properties

Chemistry informtion about  Mikamycin B (3131-03-1) is:
Synonyms: mikamycin B ; N-[(3-Hydroxy-2-pyridinyl)carbonyl]cyclo(L-Thr*-D-Abu-L-Pro-N-methyl-4-(dimethylamino)-L-Phe-4-oxo-L-2-piperidinecarbonyl-L-phenyl Gly-) ; Ostreogrycin B;Pristinamycin IA;Streptogramin B
MW: 866.957860 g/mol
MF: C45H54N8O10
Density: 1.38 g/cm3
Flash Point: 680.8 °C
Boiling Point: 1202.1 °C at 760 mmHg 
Enthalpy of Vaporization: 184.6 kJ/mol
Following is the molecular structure of  Mikamycin B (3131-03-1) is:

Mikamycin B Toxicity Data With Reference

1.    

orl-mus LD50:200 mg/kg

    85FZAT    Index of Antibiotics from Actinomycetes Umezawa, H., et al., eds.,Tokyo, Japan.: University of Tokyo Press,1967,750.
2.    

ipr-mus LD50:350 µg/kg

    85ERAY    Antibiotics: Origin, Nature, and Properties. 1 (1978),367.
3.    

scu-mus LD50:200 mg/kg

    85FZAT    Index of Antibiotics from Actinomycetes Umezawa, H., et al., eds.,Tokyo, Japan.: University of Tokyo Press,1967,750.

Mikamycin B Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
RIDADR: 3172
HazardClass: 6.1(b)
PackingGroup: III

Mikamycin B Specification

 Mikamycin B (3131-03-1) is a specific streptogramin group B antibiotic produced by Streptomyces graminofaciens and other bacteria.

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