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N,N,N',N'-Tetramethylbenzidine

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N,N,N',N'-Tetramethylbenzidine

EINECS 206-676-5
CAS No. 366-29-0 Density 1.041g/cm3
PSA 6.48000 LogP 3.48560
Solubility Melting Point 193 - 195 C
Formula C16H20 N2 Boiling Point 387.1°Cat760mmHg
Molecular Weight 240.348 Flash Point 173.4°C
Transport Information 25kgs Appearance white to brown powder
Safety Risk Codes 36/37/38-40-22
Molecular Structure Molecular Structure of 366-29-0 (N,N,N',N'-TETRAMETHYLBENZIDINE) Hazard Symbols Xi,Xn
Synonyms

Benzidine,N,N,N',N'-tetramethyl- (6CI,8CI); [1,1'-Biphenyl]-4,4'-diamine,N,N,N',N'-tetramethyl- (9CI); 4,4'-Bis(N,N-dimethylamino)biphenyl;4,4'-Bis(dimethylamino)-1,1'-biphenyl; 4,4'-Bis(dimethylamino)biphenyl;N,N,N',N'-Tetramethyl-p,p'-benzidine;N,N,N',N'-Tetramethyl[1,1'-biphenyl]-4,4'-diamine;N,N,N',N'-Tetramethylbenzidine; N,N-Dimethyl-(4'-(dimethylamino)biphenyl-4-yl)amine;NSC 433; TMB

Article Data 163

N,N,N',N'-Tetramethylbenzidine Chemical Properties

IUPAC Name:  4-(4-dimethylaminophenyl)-N,N-dimethylaniline
Synonyms: (1,1'-Biphenyl)-4,4'-diamine, N,N,N',N'-tetramethyl- ; 4,4'-Bis(N,N-dimethylamino)biphenyl ; AI3-61957 ; CCRIS 1000 ; EINECS 206-676-5 ; N,N,N',N'-Tetramethyl-p,p'-benzidine ; N,N,N',N'-Tetramethylbenzidine ; NSC 433 
Systematic Name: (1,1'-Biphenyl)-4,4'-diamine, N,N,N',N'-tetramethyl- ;  (1,1'-Biphenyl)-4,4'-diamine, N4,N4,N4',N4'-tetramethyl- ; Benzidine, N,N,N',N'-tetramethyl- ; N,N,N',N'-Tetramethyl-(1,1'-biphenyl)-4,4'-diamine ; N,N,N',N'-Tetramethylbenzidine
Canonical SMILES: CN(C)C1=CC=C(C=C1)C2=CC=C(C=C2)N(C)C
InChI: InChI=1S/C16H20N2/c1-17(2)15-9-5-13(6-10-15)14-7-11-16(12-8-14)18(3)4/h5-12H,1-4H3
InChIKey: YRNWIFYIFSBPAU-UHFFFAOYSA-N
Molecular Formula: C16H20N2
Molecular Weight: 240.34
EINECS: 206-676-5
Density: 1.041 g/cm3
Melting Point: 193-195 °C(lit.)
Flash Point: 8.9 °C 
Boiling Point: 387.1 °C at 760 mmHg
Surface Tension: 41.2 dyne/cm
Flash Point: 173.4 °C
Enthalpy of Vaporization: 63.61 kJ/mol
Vapour Pressure: 3.38E-06 mmHg at 25°C 
Product Categories: Organics ; ELISA Substrates ; Peroxidase ; Powders
Following is the molecular structure of N,N,N',N'-Tetramethylbenzidine (CAS NO.366-29-0) is:

N,N,N',N'-Tetramethylbenzidine Toxicity Data With Reference

1.    

mma-sat 10 nmol/plate

    EMMUEG    Environmental and Molecular Mutagenesis. 10 (1987),263.

N,N,N',N'-Tetramethylbenzidine Consensus Reports

Reported in EPA TSCA Inventory.

N,N,N',N'-Tetramethylbenzidine Safety Profile

Safty information about N,N,N',N'-Tetramethylbenzidine (CAS NO.366-29-0) is:
Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.
Hazard Codes:
IrritantXi,Xn
Risk Statements:
R36/37/38:Irritating to eyes, respiratory system and skin. 
R40:Limited evidence of a carcinogenic effect. 
R22:Harmful if swallowed.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing. 
S36/37:Wear suitable protective clothing and gloves.
WGK Germany: 3
RTECS: DD1752100

N,N,N',N'-Tetramethylbenzidine Specification

 N,N,N',N'-Tetramethylbenzidine (CAS NO.366-29-0) is stable solid and it incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents. 
First Aid Measures:
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.
Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation: Remove from exposure and move to fresh air immediately. 
Handling and Storage:
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage: Store in a cool, dry place. Keep container closed when not in use.

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