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Cas Database |
| Name |
N-Nitrosodi-n-propylamine |
EINECS | N/A | |
| CAS No. | 621-64-7 | Density | 0.92 | |
| PSA | 32.67000 | LogP | 1.78980 | |
| Solubility | 9,900 mg/L at 25 °C (Mirvish et al., 1976) | Melting Point |
N/A |
|
| Formula | C6H14 N2 O | Boiling Point | 113 °C / 40mmHg | |
| Molecular Weight | 130.19 | Flash Point | 10 °C | |
| Transport Information | N/A | Appearance | N/A | |
| Safety | Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic data. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITROSAMINES. | |||
Analytical Methods: | For occupational chemical analysis use OSHA: #27 or NIOSH: Nitrosamines 2522. |
Risk Codes | R45; R22; R51/53; R39/23/24/25; R23/24/25; R11 | |
| Molecular Structure |
|
Hazard Symbols |
 T, N, F
|
|
| Synonyms |
Dipropylamine,N-nitroso- (6CI,7CI,8CI); Dipropylnitrosamine; N,N-Dipropylnitrosamine;N-Nitroso-N-di-n-propylamine; N-Nitrosodi-n-propylamine;N-Nitrosodipropylamine; NSC 133 |
Article Data | 20 |
N-Nitrosodi-n-propylamine Chemical Properties
Empirical Formula: C6H14N2O
Molecular Weight: 130.1882 g/mol
EINECS: 210-698-0
Index of Refraction: 1.451
Density: 0.93 g/cm3
Flash Point: 82.6 °C
Enthalpy of Vaporization: 42.42 kJ/mol
Boiling Point: 206 °C at 760 mmHg
Vapour Pressure: 0.348 mmHg at 25 °C
Storage tempreture: 2-8 °C
Appearance: Clear to pale yellow liquid
Structure of N-Nitrosodi-n-propylamine (CAS NO.621-64-7):
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IUPAC Name: N,N-Dipropylnitrous amide
Product Categories: Nitrosamine;Alpha Sort;Amines;Chemical Class;N-OAlphabetic
N-Nitrosodi-n-propylamine Toxicity Data With Reference
| 1. | mma-sat 1 µmol/plate | GANNA2 Gann. Japanese Journal of Cancer Research. 75 (1984),8. | ||
| 2. | dns-hmn:hla 100 µmol/L | CNREA8 Cancer Research. 38 (1978),2621. | ||
| 3. | scu-ham TDLo:100 mg/kg (14D preg):NEO,TER | ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. 90 (1977),79. | ||
| 4. | orl-rat LD50:480 mg/kg | ZEKBAI Zeitschrift fuer Krebsforschung. 69 (1967),103. | ||
| 5. | scu-rat LD50:487 mg/kg | JNCIAM Journal of the National Cancer Institute. 54 (1975),937. | ||
| 6. | scu-mus LD50:689 mg/kg | ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. 90 (1977),253. | ||
| 7. | scu-ham LD50:600 mg/kg | JNCIAM Journal of the National Cancer Institute. 51 (1973),1019. |
N-Nitrosodi-n-propylamine Consensus Reports
NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 ,1978,p. 177.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 ,1978,p. 177.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program. Community Right-To-Know List. Reported in EPA TSCA Inventory.
N-Nitrosodi-n-propylamine Safety Profile
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic data. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITROSAMINES.
Hazard Codes: 
T,
N,
F
Risk Statements: 45-22-51/53-39/23/24/25-23/24/25-11
R11:Highly flammable.
R22:Harmful if swallowed.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R39:Danger of very serious irreversible effects.
R45:May cause cancer.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 53-45-61-36/37
S36/37:Wear suitable protective clothing and gloves.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S53:Avoid exposure - obtain special instructions before use.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
N-Nitrosodi-n-propylamine Standards and Recommendations
DFG MAK: Animal Carcinogen, Suspected Human Carcinogen
N-Nitrosodi-n-propylamine Analytical Methods
For occupational chemical analysis use OSHA: #27 or NIOSH: Nitrosamines 2522.
N-Nitrosodi-n-propylamine Specification
N-Nitrosodi-n-propylamine ,its cas register number is 621-64-7. It also can be called N-Nitroso-N-propyl-1-propanamine ; Oryzalin metabolite ; N-Nitroso-N-propylpropan-1-amin ;and 1-Propanamine, N-nitroso-N-propyl- . N-Nitrosodi-n-propylamine (CAS NO.621-64-7) is a nitrated amine derivative, and some may burn but none ignite readily.
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