3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl5-[2-[methyl(phenylmethyl)amino]ethyl] ester

IUPAC Name: 3-O-[2-[benzyl(methyl)amino]ethyl] 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Synonyms Methyl 2-(benzyl-methyl-amino)ethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Product Categories: Active Pharmaceutical Ingredients
Molecular Structure: m-nitrobenzaldehyde as raw materials, condensation of acetyl chloride acid methyl ester with the amino-crotonic to get 2,6 - dimethyl -4 - (Inter-nitrophenyl) -1,4 - dihydro-pyridine 3,5 - 2-carboxylic acid - (2 - chloro) ethyl -5 - methyl ester, then condensation with benzyl amine nicardipine.
Molecular Formula: C₂₆H₂₉N3O₆
Molecular Weight : 479.52
CAS NO: 55985-32-5
EINECS : 259-932-3
Mol File: 55985-32-5.mol
Melting point 136-138 ºC
Index of Refraction: 1.581
Surface Tension: 48.7 dyne/cm
Density: 1.23 g/cm³
Flash Point: 318.7 °C
Enthalpy of Vaporization: 89.75 kJ/mol
Boiling Point: 603.4 °C at 760 mmHg
Vapour Pressure: 1.63E-14 mmHg at 25°C
Appearance: Nicardipine Hydrochloride (CAS NO.55985-32-5) is yellow-green crystalline powder.

Nicardipine Hydrochloride (CAS NO.55985-32-5) is a new calcium antagonist, vasodilator,mainly used  for ischemic cerebrovascular disease and the treatment of essential hypertension.

M-Nitrobenzaldehyde as raw materials, condensation of acetyl chloride acid methyl ester with the amino-crotonic to get 2,6 - dimethyl -4 - (Inter-nitrophenyl) -1,4 - dihydro-pyridine 3,5 - 2-carboxylic acid - (2 - chloro) ethyl -5 - methyl ester, then condensation with benzyl amine  nicardipine. Get Nicardipine Hydrochloride (CAS NO.55985-32-5) .