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Nicotinic hydrazide

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Name

Nicotinic hydrazide

EINECS 209-041-0
CAS No. 553-53-7 Density 1.244g/cm3
PSA 68.01000 LogP 0.77630
Solubility Soluble in alcohol, water. Melting Point 159-161°C(lit.)
Formula C6H7 N3 O Boiling Point °Cat760mmHg
Molecular Weight 137.141 Flash Point °C
Transport Information N/A Appearance WHITE TO OFF-WHITE FINE NEEDLE-LIKE CRYST. POWDER
Safety Poison by intravenous and parenteral routes. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of NOx. Risk Codes R40;
Molecular Structure Molecular Structure of 553-53-7 (NICOTINIC ACID HYDRAZIDE) Hazard Symbols Xn
Synonyms

Nicotinicacid, hydrazide (6CI,7CI,8CI); (3-Pyridylcarbonyl)hydrazine;3-Pyridinecarbohydrazide; 3-Pyridinecarboxylic hydrazide; 3-Pyridoylhydrazine;INHd 37; N-Aminopyridine-3-carboxamide; NSC 18775; NSC 36088; NSC 41703;Niazid; Nicotinic hydrazide; Nicotinohydrazide; Nicotinoyl hydrazide;Nicotinoylhydrazine; Nicotinyl hydrazide; Nicotinylhydrazine

Article Data 115

Nicotinic hydrazide Chemical Properties

MF: C6H7N3O
MW: 137.14
EINECS: 209-041-0
Density: 1.244 g/cm3
Index of Refraction: 1.583
Melting Point: 159-161 °C(lit.)
IUPAC Name: Pyridine-3-carbohydrazide
Appearance: white to off-white fine needle-like cryst. powder
Product Categories: Amide ; Heterocyclic Compounds
Synonyms: (3-Pyridylcarbonyl)hydrazine ; 3-Pyridinecarboxylic acid, hydrazide ; 3-Pyridinecarboxylic hydrazide ; 3-Pyridinecarboxylicacid,hydrazide ; 3-Pyridoyl Hydrazine ; 3-Pyridoylhydrazine ; 3-Pyridylcarbonylhydrazine ; Hydrazine, nicotinoyl-
Following is the molecular structure of Nicotinic acid, hydrazide (553-53-7):

Nicotinic hydrazide Toxicity Data With Reference

1.    

ivn-mus LD50:180 mg/kg

    CSLNX*    U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#04178 .
2.    

par-mus LDLo:100 mg/kg

    CBCCT*    “Summary Tables of Biological Tests“ National Research Council Chemical-Biological Coordination Center. 7 (1955),691.

Nicotinic hydrazide Safety Profile

Poison by intravenous and parenteral routes. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of NOx
Safety Information of Nicotinic acid, hydrazide (553-53-7):
Hazard Codes: Xi
Xi: Irritant
Risk Statements: 36/37/38
36/37/38: Irritating to eyes, respiratory system and skin 
Safety Statements: 22-26-36/37/39
22:  Do not breathe dust 
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39:  Wear suitable protective clothing, gloves and eye/face protection 
RIDADR: UN2811
WGK Germany: 3
RTECS: QT1750000
HazardClass: 6.1
PackingGroup: III

Nicotinic hydrazide Analytical Methods

AnalyticalMethods of Nicotinic acid, hydrazide (553-53-7): HPLC,NMR

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