Basic information
- Name:
Oxolinic acid
- CAS No.:
14698-29-4
- Molecular Structure:

- Formula:
- C13H11NO5
- Synonyms:
- 1-Ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylicacid;5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid;Emyrenil;Inoxyl;Ossian;Oxoboi;Prodoxal;Starner;Starner 20WP;Urinox;Uritrate;Uroxol;W 4565;Galantamine Hydrobromide;
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Chemistry
Molecular Structure of Oxolinic acid (CAS NO.14698-29-4):

IUPAC Name: 5-Ethyl- 8-oxo- 5,8-dihydro [1,3] dioxolo [4,5-g] quinoline- 7-carboxylic acid
Molecular formula: C13H11NO5
Molecular Weight: 261.23
Density: 1.483 g/cm3
Melting point: 314-316°C (dec.)
Boiling point: 473.2 °C at 760 mmHg
Flash point: 240 °C
Merck: 13,7014
Stability: Stable. Combustible
Index of Refraction: 1.638
Molar Refractivity: 63.31 cm3
Molar Volume: 176.1 cm3
Polarizability: 25.1*10-24cm3
Surface Tension: 63.9 dyne/cm
Enthalpy of Vaporization: 77.57 kJ/mol
Vapour Pressure: 9.24E-10 mmHg at 25°C
Appearance: crystalline solid
EINECS: 238-750-8
Product Categories: Heterocyclic Compounds; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals; veterinary medicine, APIs, pharmaceutical raw material
InChI
InChI=1/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)
Smiles
c12c(cc3OCOc3c2)c(c(C(O)=O)cn1CC)=O
Toxicity Data With Reference
| 1. | mmo-esc 130 µg/L | AMACCQ Antimicrobial Agents and Chemotherapy. 17 (1980),763. | ||
| 2. | oms-esc 50 mg/L | EJBCAI European Journal of Biochemistry. 62 (1976),491. | ||
| 3. | orl-rat LD50:525 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185. | ||
| 4. | skn-rat LD50:>2 g/kg | JPIFAN Japan Pesticide Information.(55)(1989),21. | ||
| 5. | orl-mus LD50:1890 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185. |
Safety Profile
Moderately toxic by ingestion. Low toxicity by skin contact. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:
Xn
Risk Statements:
R22:Harmful if swallowed.
Safety Statements:
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
WGK Germany: 3
RTECS: JI5075000
F: 10
Specification
Oxolinic acid , with CAS number of 14698-29-4, can be called 1-ethyl-6,7-methylenedioxo-4-quinoline-3-carboxlicacid ; 1-ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylicacid ; 5-g)quinoline-7-carboxylicacid,5-ethyl-5,8-dihydro-8-oxo-3-dioxolo(4;5-g]quinoline-7-carboxylicacid,5-ethyl-5,8-dihydro-8-oxo-3-dioxolo[4 ; dioxacin ; emyrenil ; gramurin ; 1-ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylicacid . It is a crystalline solid, used as quinolone antibacterial.
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