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Basic information

  • Name:
  • Oxolinic acid

  • CAS No.:
  • 14698-29-4

  • Formula:
  • C13H11NO5
  • Synonyms:
  • 1-Ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylicacid;5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid;Emyrenil;Inoxyl;Ossian;Oxoboi;Prodoxal;Starner;Starner 20WP;Urinox;Uritrate;Uroxol;W 4565;Galantamine Hydrobromide;
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Chemistry

Molecular Structure of Oxolinic acid (CAS NO.14698-29-4):

IUPAC Name: 5-Ethyl- 8-oxo- 5,8-dihydro [1,3] dioxolo [4,5-g] quinoline- 7-carboxylic acid
Molecular formula: C13H11NO5
Molecular Weight: 261.23
Density: 1.483 g/cm3
Melting point: 314-316°C (dec.)
Boiling point: 473.2 °C at 760 mmHg
Flash point: 240 °C
Merck: 13,7014
Stability: Stable. Combustible
Index of Refraction: 1.638
Molar Refractivity: 63.31 cm3
Molar Volume: 176.1 cm3
Polarizability: 25.1*10-24cm3
Surface Tension: 63.9 dyne/cm
Enthalpy of Vaporization: 77.57 kJ/mol
Vapour Pressure: 9.24E-10 mmHg at 25°C
Appearance: crystalline solid
EINECS: 238-750-8
Product Categories: Heterocyclic Compounds; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals; veterinary medicine, APIs, pharmaceutical raw material
InChI
InChI=1/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)
Smiles
c12c(cc3OCOc3c2)c(c(C(O)=O)cn1CC)=O

Toxicity Data With Reference

1.    

mmo-esc 130 µg/L

    AMACCQ    Antimicrobial Agents and Chemotherapy. 17 (1980),763.
2.    

oms-esc 50 mg/L

    EJBCAI    European Journal of Biochemistry. 62 (1976),491.
3.    

orl-rat LD50:525 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 18 (1971),185.
4.    

skn-rat LD50:>2 g/kg

    JPIFAN    Japan Pesticide Information.(55)(1989),21.
5.    

orl-mus LD50:1890 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 18 (1971),185.

Safety Profile

Moderately toxic by ingestion. Low toxicity by skin contact. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: HarmfulXn
Risk Statements:
R22:Harmful if swallowed.
Safety Statements:
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
WGK Germany: 3
RTECS: JI5075000
F: 10

Specification

  Oxolinic acid , with CAS number of 14698-29-4, can be called 1-ethyl-6,7-methylenedioxo-4-quinoline-3-carboxlicacid ; 1-ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylicacid ; 5-g)quinoline-7-carboxylicacid,5-ethyl-5,8-dihydro-8-oxo-3-dioxolo(4;5-g]quinoline-7-carboxylicacid,5-ethyl-5,8-dihydro-8-oxo-3-dioxolo[4 ; dioxacin ; emyrenil ; gramurin ; 1-ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylicacid . It is a crystalline solid, used as quinolone antibacterial.

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