Welcome to LookChem.com Sign In | Join Free   Post buying lead  Chemical Tools
Post Buying Lead

Basic information

  • Name:
  • Benzamide,2,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxy-

  • Superlist Name:
  • Oxyclozanide
  • CAS No.:
  • 2277-92-1

  • Formula:
  • C13H6Cl5NO3
  • Synonyms:
  • Salicylanilide,3,3',5,5',6-pentachloro-2'-hydroxy- (7CI,8CI);3,3',5,5',6-Pentachloro-2,2'-dihydroxybenzanilide;3,3',5,5',6-Pentachloro-2'-hydroxysalicylanilide;3,5,6,3',5'-Pentachloro-2,2'-dihydroxybenzanilide;Diplin;ICI 46638;Oxyclozanid;Zanil;Zanilox;
Home > Hot Product_List > Oxyclozanide
Supplier Location:
India(16)China (Mainland)(15)Denmark(1)United States(1)
Business Type:
Importer/Exporter(22)Lab/Research institutions(1)
Certificates:
ISO(1)Production License(0)

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Specification

The Oxyclozanide is an organic compound with the formula C13H6Cl5NO3. The IUPAC name of this chemical is 2,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide. With the CAS registry number 2277-92-1, it is also named as 2,2'-Dihydroxy-3,3',5,5',6-pentachlorobenzanilide. The product's classification codes are Anthelmintics; Anti-Infective Agents; Antiparasitic Agents; Antiplatyhelmintic agents; Drug / Therapeutic Agent. Besides, it should be stored at temperature of 0 - 6 °C. It is a salicylanilide anthelmintic. It is used in the treatment and control of Fascioliasis in ruminants mainly domestic animals like Cattle, Sheep and Goats.

Physical properties about Oxyclozanide are: (1)ACD/LogP: 8.67; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 8.16; (4)ACD/LogD (pH 7.4): 6.19; (5)ACD/BCF (pH 5.5): 706340; (6)ACD/BCF (pH 7.4): 7634.49; (7)ACD/KOC (pH 5.5): 382470.31; (8)ACD/KOC (pH 7.4): 4133.94; (9)#H bond acceptors: 4; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 38.77 Å2; (13)Index of Refraction: 1.722; (14)Molar Refractivity: 89.06 cm3; (15)Molar Volume: 224.9 cm3; (16)Polarizability: 35.3×10-24cm3; (17)Surface Tension: 72.4 dyne/cm; (18)Density: 1.784 g/cm3; (19)Flash Point: 223.5 °C; (20)Enthalpy of Vaporization: 73.12 kJ/mol; (21)Boiling Point: 446 °C at 760 mmHg; (22)Vapour Pressure: 1.43E-08 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
It is harmful if swallowed and very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, this chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable protective clothing. This material and its container must be disposed of as hazardous waste.

You can still convert the following datas into molecular structure:
(1)SMILES: Clc2c(C(=O)Nc1cc(Cl)cc(Cl)c1O)c(O)c(Cl)cc2Cl
(2)InChI: InChI=1/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22)
(3)InChIKey: JYWIYHUXVMAGLG-UHFFFAOYAW
(4)Std. InChI: InChI=1S/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22)
(5)Std. InChIKey: JYWIYHUXVMAGLG-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cattle LDLo oral 60mg/kg (60mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: COMA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Veterinary Record. Vol. 78, Pg. 267, 1966.
domestic animals - goat/sheep LDLo intravenous 10mg/kg (10mg/kg)   Veterinary Record. Vol. 78, Pg. 267, 1966.
domestic animals - goat/sheep LDLo oral 60mg/kg (60mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Veterinary Record. Vol. 78, Pg. 267, 1966.
rat LD50 oral 1gm/kg (1000mg/kg)   Nature. Vol. 210, Pg. 744, 1966.

©2008 LookChem.com,License:ICP NO.:Zhejiang10014259

[Hangzhou]86-571-85317600,85317603,85317620