Basic Information | Post buying leads | Suppliers |
Name |
POTASSIUM CANRENOATE |
EINECS | 218-554-9 |
CAS No. | 2181-04-6 | Density | g/cm3 |
PSA | 77.43000 | LogP | 2.55550 |
Solubility | Very soluble in water; soluble in alcohol; insoluble in coloroform and | Melting Point |
N/A |
Formula | C22H30 O4 . K | Boiling Point | °Cat760mmHg |
Molecular Weight | 396.568 | Flash Point | °C |
Transport Information | N/A | Appearance | Light yellow to tan powder |
Safety | Poison by intravenous, subcutaneous, and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. A steroid. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes of K2O. | Risk Codes | R22 |
Molecular Structure | Hazard Symbols | ||
Synonyms |
17a-Pregna-4,6-diene-21-carboxylicacid, 17-hydroxy-3-oxo-, monopotassium salt (8CI); 17a-Pregna-4,6-diene-21-carboxylicacid, 17-hydroxy-3-oxo-, potassium salt (7CI); Pregna-4,6-diene-21-carboxylicacid, 17-hydroxy-3-oxo-, monopotassium salt, (17a)- (9CI); 17-Hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylicacid potassium salt; Aldadiene Kalium; Aldadiene potassium; Aldadiene potassiumsalt; CB 8109; Canrenoate potassium; Kanrenol; MF 465 a; Potassium17-hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylate; Potassium 3-(17b-hydroxy-3-oxoandrosta-4,6-dien-17-yl)propionate;Potassium 3-(3-oxo-17b-hydroxy-4,6-androstadien-17a-yl)propionate; Potassium aldadiene; Potassium canrenoate; Potassium b-(3-oxo-17b-hydroxyandrosta-4,6-dien-17a-yl)propionate; SC 14266; SC14266/371; Soldactona; Soldactone; Soludactone; Venactone |
Product Name: Potassium 3-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate
Synonyms: Aldadiene-potassium ; Canrenoate Potassium ;Canrenone free acid potassium salt ; Potassium 17-hydroxy-3-oxo-17alpha-pregna-4,6-diene-21-carboxylate ; Potassium 17-Hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylate ; Potassium 3-(17-beta-hydroxy-3-oxoandrosta-4,6-dien-17-yl)propionate ; Potassium 3-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate (non-preferred name)
Molecular Structure :
Molecular Formula : C22H29KO4
Molecular Weight : 396.56
CAS NO: 2181-04-6
EINECS: 218-554-9
Appearance: Potassium canrenoate (CAS NO.2181-04-6) is color light yellow to tan powder.
Potassium canrenoate (CAS NO.2181-04-6) is for the metabolites of spironolactone Canrenoate acid potassium salt, role similar to spironolactone, but a lesser role in the feminization of male breast, it can be used as alternative medicine, mainly for heart failure, edema, and cirrhosis with ascites.
1. | mic-mus:lym 150 mg/L | ARTODN Archives of Toxicology. 61 (1988),201. | ||
2. | orl-rat LD50:650 mg/kg | NICHAS Nichidai Igaku Zasshi. 36 (1977),7. | ||
3. | ipr-rat LD50:183 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811. | ||
4. | scu-rat LD50:160 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811. | ||
5. | ivn-rat LD50:112 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811. | ||
6. | orl-mus LD50:740 mg/kg | NICHAS Nichidai Igaku Zasshi. 36 (1977),7. | ||
7. | ipr-mus LD50:140 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 149 (1964),8. | ||
8. | scu-mus LD50:165 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811. | ||
9. | ivn-mus LD50:125 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811. |
Poison by intravenous, subcutaneous, and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. A steroid. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes of K2O.
Hazard Codes Xn
Risk Statements 22
R22: Potassium canrenoate (CAS NO.2181-04-6) is harmful if swallowed.
Safety Statements 36
S36:Wear suitable protective clothing.
WGK Germany 3
RTECS TU3500000