Basic information
- Name:
Polyvinylpyrrolidone - iodine complex
- Superlist Name:
- Povidone-iodine
- CAS No.:
25655-41-8
- Molecular Structure:
- Formula:
- (C6H9NO)x. xI2
- Synonyms:
- Tegodyne;Poly(1-(2-Oxo-1-Pyrrolidinyl)Ethylene)-Iodine Complex;Povidoneiodine;1-Ethenyl-2-pyrrolidinone homopolymer compound with iodine;1-Vinyl-2-pyrrolidinone polymer, compd. with iodine;2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine;Argentyne;
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Chemistry
Povidone iodine's Molecular formula: (C6H9NO)n·xI
Povidone iodine's Molar mass: variable
Synonyms: 2-Pyrrolidinone; 1-ethenyl-homopolymer; compd. with iodine; Betadine; Efo-dine; Polyvinylpyrrolidone-iodine complex; PVP-I(Povidone-iodine/solution)
Povidone-iodine (PVP-I) is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.
Povidone iodine's Molar mass: variable
Synonyms: 2-Pyrrolidinone; 1-ethenyl-homopolymer; compd. with iodine; Betadine; Efo-dine; Polyvinylpyrrolidone-iodine complex; PVP-I(Povidone-iodine/solution)
Povidone-iodine (PVP-I) is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.
History
Povidone iodine was discovered at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. They carried out in vitro tests to demonstrate antibacterial activity, and found that the complex was less toxic than tincture of iodine in mice. Human clinical trials showed the product to be superior to other iodine formulations.
It was first sold in 1955, and has since become the universally preferred iodine disinfectant.
Uses
Povidone iodine has been broadly used for the prevention and treatment of skin infections, and the treatment of wounds.
Povidone iodine has found broad application in medicine as a surgical scrub; for pre- and post-operative skin cleansing; for the treatment and prevention of infections in wounds, ulcers, cuts and burns; for the treatment of infections in decubitus ulcers and stasis ulcers; in gynecology for vaginitis associated with candidal, trichomonal or mixed infections.
Povidone iodine has found broad application in medicine as a surgical scrub; for pre- and post-operative skin cleansing; for the treatment and prevention of infections in wounds, ulcers, cuts and burns; for the treatment of infections in decubitus ulcers and stasis ulcers; in gynecology for vaginitis associated with candidal, trichomonal or mixed infections.
Toxicity Data With Reference
RTECS TR1579600
Safety Profile
Safety Statements 24/25-22
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