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Basic information

  • Name:
  • 1-Naphthaleneheptanoicacid, 1,2,6,7,8,8a-hexahydro-b,d,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-,(bR,dR,1S,2S,6S,8S,8aR)-

  • Superlist Name:
  • Pravastatin
  • CAS No.:
  • 81093-37-0

  • Formula:
  • C23H36O7
  • Synonyms:
  • 1-Naphthaleneheptanoicacid, 1,2,6,7,8,8a-hexahydro-b,d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-,[1S-[1a(bS*,dS*),2a,6a,8b(R*),8aa]]-;3b-Hydroxycompactin;Eptastatin;Mevalothin;Pravastatin acid;
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Chemistry

Molecular Structure of Pravastatin (CAS NO.81093-37-0):

Molecular Formula: C23H36O7
Molecular Weight: 424.5277
IUPAC Name: (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-Hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
Synonyms of Pravastatin (81093-37-0): Pravastatin [INN:BAN] ; CCRIS 7557 ; Pravastatina ; Pravastatina [Spanish] ; Pravastatine ; Pravastatine [French] ; Pravastatinum ; Pravastatinum [Latin] ; UNII-KXO2KT9N0G ; 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-((2S)-2-methyl-1-oxobutoxy)-, (betaR,deltaR,1S,2S,6S,8S,8aR)- ; 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betas*,deltas*),2alpha,6alpha,8beta(R*),8aalpha))-
CAS NO: 81093-37-0
Classification Code: Anticholesteremic agents ; Antilipemic Agents ; Antimetabolites ; Enzyme Inhibitors ; Hydroxymethylglutaryl-CoA reductase inhibitors
Melting point: 171.2-173 °C 
Index of Refraction: 1.554
Molar Refractivity: 111.98 cm3
Molar Volume: 349.1 cm3
Surface Tension: 53.9 dyne/cm
Density: 1.21 g/cm3
Flash Point: 213.2 °C
Enthalpy of Vaporization: 107.45 kJ/mol
Boiling Point: 634.5 °C at 760 mmHg
Vapour Pressure: 9.15E-19 mmHg at 25°C

Uses

 Pravastatin (81093-37-0) is commonly used for lowering blood pressure, cholesterol drugs.

Safety Profile

Hazard Codes of Pravastatin (81093-37-0): FlammableF,CorrosiveC
Risk Statements: 11-34 
R11:Highly flammable. 
R34:Causes burns.
Safety Statements: 16-26-36/37/39-45 
S16:Keep away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

Specification

 Pravastatin (CAS NO.81093-37-0) is a white to yellowish white powder or crystalline powder, odorless, bitter taste.As a reductase inhibitor, for a variety of models have reduced the role of hyperlipidemia, for lowering blood pressure, cholesterol, from the micro-organisms to be hydroxide.

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