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Pirimicarb

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Pirimicarb

EINECS 245-430-1
CAS No. 23103-98-2 Density 1.146 g/cm3
PSA 58.56000 LogP 1.21980
Solubility 3060 mg l-1 Melting Point 90.5°C
Formula C11H18N4O2 Boiling Point 373.4 °C at 760 mmHg
Molecular Weight 238.29 Flash Point 179.6 °C
Transport Information UN 2811 Appearance white crystal
Safety 22-37-45-60-61-36-26-16 Risk Codes 25-50/53-36-20/21/22-11
Molecular Structure Molecular Structure of 23103-98-2 (Pirimicarb) Hazard Symbols ToxicT; DangerousN; HarmfulXn; FlammableF
Synonyms

Carbamicacid, dimethyl-, 2-(dimethylamino)-5,6-dimethyl-4-pyrimidinyl ester (8CI,9CI);4-Pyrimidinol, 2-(dimethylamino)-5,6-dimethyl-, dimethylcarbamate (ester)(8CI);2-Dimethylamino-5,6-dimethyl-4-pyrimidinyl dimethylcarbamate;2-Dimethylamino-5,6-dimethylpyrimidin-4-yl N,N-dimethylcarbamate;5,6-Dimethyl-2-dimethylamino-4-dimethylcarbamoyloxypyrimidine;Aphox;Fernos;PP 062;Pirimix;Pirimor;Pirimor G;Pirimor Granulate;Pyrimor;

Article Data 5

Pirimicarb Consensus Reports

EPA Genetic Toxicology Program.

Pirimicarb Specification

The Pirimicarb, with the CAS registry number 23103-98-2 and EINECS registry number 245-430-1, has the systematic name of 2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl dimethylcarbamate. It is also called carbamic acid, N,N-dimethyl-, 2-(dimethylamino)-5,6-dimethyl-4-pyrimidinyl ester. And the molecular formula of this chemical is C11H18N4O2.

The physical properties of Pirimicarb are as following: (1)ACD/LogP: 1.70; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.68; (4)ACD/LogD (pH 7.4): 1.7; (5)ACD/BCF (pH 5.5): 11.11; (6)ACD/BCF (pH 7.4): 11.57; (7)ACD/KOC (pH 5.5): 192.74; (8)ACD/KOC (pH 7.4): 200.75; (9)#H bond acceptors: 6; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 58.56 Å2; (13)Index of Refraction: 1.548; (14)Molar Refractivity: 66.09 cm3; (15)Molar Volume: 207.8 cm3; (16)Polarizability: 26.2×10-24cm3; (17)Surface Tension: 45.5 dyne/cm; (18)Density: 1.146 g/cm3; (19)Flash Point: 179.6 °C; (20)Enthalpy of Vaporization: 62.07 kJ/mol; (21)Boiling Point: 373.4 °C at 760 mmHg; (22)Vapour Pressure: 8.99E-06 mmHg at 25°C.

Uses and preparation of Pirimicarb: It is a carbamate insecticide used to control aphids on vegetable, cereal and orchard crops by inhibiting acetylcholinesterase activity. This chemical can be prepared via the common systematic method of carbamate chemicals for agriculture.

Pirimicarb can be prepared via the common systematic method of carbamate chemicals for agriculture

You should be cautious while dealing with this chemical. It is a highly flammable chemcial which is harmful by inhalation, in contact with skin and if swallowed. It is toxic if swallowed, and irritates eyes. What's more, it is very toxic to aquatic organisms, and may cause long-term adverse effects in the aquatic environment. Therefore, you had better take the following instructions: Wear suitable protective clothing, and in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice; Keep away from sources of ignition - No smoking; Do not breathe dust; This material and/or its container must be disposed of as hazardous waste; Avoid release to the environment. Refer to special instructions safety data sheet; In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(Oc1nc(nc(c1C)C)N(C)C)N(C)C
(2)InChI: InChI=1/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3
(3)InChIKey: YFGYUFNIOHWBOB-UHFFFAOYAL

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 30mg/kg (30mg/kg)   Journal of Agricultural and Food Chemistry. Vol. 24, Pg. 136, 1976.
chicken LD50 oral 25mg/kg (25mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 184, 1976.
dog LD50 oral 100mg/kg (100mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 184, 1976.
duck LD50 oral 17200ug/kg (17.2mg/kg)   Pesticide Manual. Vol. 9, Pg. 690, 1991.
mouse LD50 oral 68mg/kg (68mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(4), Pg. 8, 1980.
pigeon LD50 oral 20mg/kg (20mg/kg)   Journal of Agricultural and Food Chemistry. Vol. 24, Pg. 136, 1976.
quail LD50 oral 54mg/kg (54mg/kg)   Journal of Agricultural and Food Chemistry. Vol. 29, Pg. 779, 1981.
rabbit LDLo skin 900mg/kg (900mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(4), Pg. 8, 1980.
rat LD50 oral 100mg/kg (100mg/kg)   Archives of Toxicology, Supplement. Vol. 4, Pg. 449, 1980.
rat LD50 skin > 500mg/kg (500mg/kg)   Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 60, 1978.

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