Basic information
- Name:
Piroxicam
- CAS No.:
36322-90-4
- Molecular Structure:
- Formula:
- C15H13N3O4S
- Synonyms:
- (4-Hydroxy-2-methyl-1,1-dioxobenzo[e]1,2-thiazin-3-yl)-N-(2-pyridyl)carboxamide;Prestwick_573;Piroxicam (JP14/USP);CP 16171;Feldene;Roxicam;4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide, 1,1-dioxide;Piroxicam [USAN:BAN:INN:JAN];2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide;Piroftal;Pyroxycam;BAXO;Feldene (TN);Piroxicamum [INN-Latin];4-Hydroxy-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide;4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid [German];
Other Products
- Titanium DioxideCarbon black Glutathione Adenosine Cable pulling lubricant
- 52482-62-98-butan-2-yl-1,3,7-trimethyl-purine-2,6-dione
- 5731-10-24'-Fluorobiphenyl-4-carboxylic acid
- 10128-91-3Methyl 2-oxo-1,2-dihydro-3-pyridinecarboxylate
- 39802-78-32'-Chlorobiphenyl-4-carbaldehyde
- 111174-59-5Alcohols, C8-16, reaction products with phosphorus oxide (P2O5)
- 7554-28-1D-(+)-Malic acid diethyl ester
- 7682-14-6N-ACETYL-DL-2-AMINO-N-BUTYRIC ACID
- 114176-54-4ethyl (NZ)-N-[[2-(6-chloropyrazin-2-yl)hydrazinyl]methylidene]carbamate
- 15833-00-82-(2-Aminophenyl)propan-2-ol
- 1550-27-21-chloro-2-nitro-4-(trifluoromethylsulfonyl)benzene
- 76-46-02-(2-Hex-1-ynylcyclohexyl)isoindole-1,3-Dione
- 31738-10-06,16B-DIMETHYL-20-OXO-11B,17A,21-TRIOL-2-(P-FLUOROPHENYL)PREGNA-4,6-DIENO-(3,2-
- 697-37-01-prop-1-ynylcyclohexan-1-ol
- 175135-19-05-morpholin-4-yl-2-nitro-phenolate
- 22255-10-3[(3S,6aR,6bS,8aR,11R,12S,12aS,14aS,14bS)-4,4,6a,6b,8a,11,12,14b-octamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picen-3-yl] hexadecanoate
- Refine Suppliers
- Do you want your product ranking ahead? Know what is 'Top Seller'!
- Supplier Location:
China (Mainland)(62)
India(12)
United States(11)
Italy(3)
Germany(2)
Switzerland(1)
Brazil(1)
- Business Type:
- Importer/Exporter(66)Lab/Research institutions(4)Manufacturers(1)Other(1)
- Certificates:
- ISO(3)Production License(0)
Please post your buying leads,so that our qualified suppliers
will soon contact you!
*Required Fields
Chemistry
Empirical Formula: C15H13N3O4S
Molecular Weight: 331.3464 g/mol
EINECS: 252-974-3
Index of Refraction: 1.714
Density: 1.563 g/cm3
Melting point: 198-200 °C
Storage tempreture: 2-8 °C
Appearance: Off-white to pale yellow solid
Structure of Piroxicam (CAS NO.36322-90-4):
IUPAC Name: (3E)-3-[Hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxobenzo[e]thiazin-4-one
Product Category of Piroxicam (CAS NO.36322-90-4): Active Pharmaceutical Ingredients;APIs;Piroxicam;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Lipid signaling
Uses
Piroxicam (CAS NO.36322-90-4) is used to relieve the symptoms of rheumatoid and osteoarthritis, primary dysmenorrhoea, postoperative pain; and act as an analgesic, especially where there is an inflammatory component. It is also used in veterinary medicine to treat certain neoplasias expressing cyclooxygenase receptors, such as bladder, colon, and prostate cancers.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| child | TDLo | oral | 7143ug/kg (7.143mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BLOOD: APLASTIC ANEMIA | South African Medical Journal. Vol. 66, Pg. 31, 1984. |
| dog | LD50 | oral | 108mg/kg (108mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 4639, 1980. |
| guinea pig | LD50 | oral | 388mg/kg (388mg/kg) | Archives of Toxicology, Supplement. Vol. 7, Pg. 365, 1984. | |
| hamster | LD50 | oral | 170mg/kg (170mg/kg) | Archives of Toxicology, Supplement. Vol. 7, Pg. 365, 1984. | |
| man | LDLo | oral | 3714mg/kg/13D (3714mg/kg) | BLOOD: AGRANULOCYTOSIS SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE" | New England Journal of Medicine. Vol. 309, Pg. 795, 1983. |
| man | TDLo | oral | 52mg/kg/26W-I (52mg/kg) | Annals of Internal Medicine. Vol. 99, Pg. 282, 1983. | |
| man | TDLo | oral | 7636mg/kg/6W- (7636mg/kg) | KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS | American Journal of Nephrology. Vol. 5, Pg. 142, 1985. |
| monkey | LD50 | oral | 1gm/kg (1000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 4639, 1980. |
| mouse | LD50 | intraperitoneal | 290mg/kg (290mg/kg) | Russian Pharmacology and Toxicology Vol. 49, Pg. 98, 1986. | |
| mouse | LD50 | oral | 250mg/kg (250mg/kg) | European Patent Application. Vol. #0079639, | |
| mouse | LD50 | subcutaneous | 300mg/kg (300mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 4639, 1980. |
| rat | LD50 | intraperitoneal | 335mg/kg (335mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 4639, 1980. |
| rat | LD50 | oral | 216mg/kg (216mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 1714, 1978. | |
| rat | LD50 | rectal | 400mg/kg (400mg/kg) | BEHAVIORAL: ANALGESIA | Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 87, 1981. |
| rat | LD50 | skin | > 5gm/kg (5000mg/kg) | Yakkyoku. Pharmacy. Vol. 37(11), Pg. -, 1986. | |
| rat | LD50 | subcutaneous | 148mg/kg (148mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 4639, 1980. |
| women | LDLo | oral | 2400ug/kg (2.4mg/kg) | LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)" LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED" KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION | British Medical Journal. Vol. 293, Pg. 540, 1986. |
| women | TDLo | oral | 400ug/kg (0.4mg/kg) | SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | Allergy. Vol. 52(Suppl, |
| women | TDLo | oral | 1200ug/kg/3D- (1.2mg/kg) | SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | Journal of Rheumatology. Vol. 11, Pg. 554, 1984. |
| women | TDLo | oral | 28mg/kg (28mg/kg) | BEHAVIORAL: HEADACHE GASTROINTESTINAL: ULCERATION OR BLEEDING FROM DUODENUM GASTROINTESTINAL: NAUSEA OR VOMITING | Acta Medica Scandinavica. Vol. 216, Pg. 335, 1984. |
Safety Profile
Hazard Codes: 
Xn, 
F
Risk Statements:
22: Harmful if swallowed
Safety Statements:
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
Specification
Piroxicam , its cas register number is 36322-90-4. It also can be called 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide .
- About us
- |
- Payment
- |
- Contact us
- |
- Links
- |
- Help Center
- |
- Disclaimer
- |
- Add to favorite
- | SiteMap
- |
- Product SiteMap
- |
- Manufacturers
- |
- Suppliers
©2008 LookChem.com,License:ICP NO.：Zhejiang10014259
[Hangzhou]86-571-85317600,85317603,85317620