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Polyethylene-polypropylene glycol

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Name

Polyethylene-polypropylene glycol

EINECS 618-355-0
CAS No. 9003-11-6 Density 1.095 g/mL at 25 °C
PSA 25.06000 LogP 0.42170
Solubility Miscible with water. Melting Point 57-61 °C
Formula HO.(C2H4O)m.(C3H6O)n.H Boiling Point 32.9 °C at 760 mmHg
Molecular Weight 102.13200 Flash Point 55.2 °C
Transport Information N/A Appearance White crystalline powder
Safety 23-24/25-45-36/37/39-26 Risk Codes 21-23/24/25-25-36/37/38
Molecular Structure Molecular Structure of 9003-11-6 (Polyethylene-polypropylene glycol) Hazard Symbols ToxicT
Synonyms

Voranol 5287;PAG 1 (polyglycol);69070-95-7;Pluronic L 44;SBU 0319;Proxanol 186;Berol TVM 370;Polyethylene oxide-polypropylene oxide copolymer;Berol 370;Adekanol NP 1200;Slovanik PV 670;Epan U 105;SK and F 18,667;Nissan Unilube 75DE3800;Dissolvan 4411;Propylene glycol, propylene oxide, ethylene oxide polymer;Methyloxirane-oxirane copolymer;Unilube 50MB168X;Epan 450;SKandF 18,667;X 427;Proxanol 224;Balab 615;Polypropylene glycol-ethylene oxide copolymer;Proxanol;ETHYLENE OXIDE, PROPYLENE OXIDE BLOCK POLYMER;Pluronic L 35;Pluronic P 85;Lupranol 2020;Voranol P 2001;TVM 370;Propylen M 12;Velvetol OE 2NT1;X 423;Prevocell EO;Adeka Carpol PH 2000;Monolan 8000E80;Poly(mixed ethylene, propylene)glycol;Pluronic P;SK&F 18,667;Oligoether L-1502-2-30;Proxanol Tsl-3;Emulgen PP 290;Ethylene oxide-propylene oxide block polymer;75H90000;Pluronic F86;Systol T 154;Pronon 104;Propylene oxide-ethylene oxide copolymer;Breox 75W270;Polyoxyethylene-oxy-propylene [French];Pluronic F 98;PPG Diol 3000EO;Poloxamer 407;Plonon 204;Polyoxyethylene polyoxypropylene;Polylon 13-5;Polykol;Nissan Unilube 25DE;Epan 750;Oxilube 50000;Nissan Unilube 50MB26X;Proxanol TsL 3;Adeka Carpol MH 500;Meroxapol 105;Pluronic F 87;Teric PE60;Pluronic-68;Regulaid;Separol 29;Pluronic C 121;Actinol P 3035;Sannix PE 75;Sannix PL 910;Poloxamer 331;Polyethylene-Pluronic L-62LF;Pronon 102;Slovanik T 630;BloaterThis heading is used only when the specific taxonomycannot be established from the original documentBloatguard;N 480;Nissan Unilube 60DP5B;53637-25-5;Polyethylene glycol, propoxylated;Exocorpol;Methyloxirane-oxirane polymer;Pluronic L 122;Epan 610;Nissan Unilube 70DP950B;Pluronic F 38;Wyandotte 7135;Ethylene glycol-propylene glycol polymer;Pepol AS 053X;Slovanik;Pluronic L 121;Laprol 1502-2-70;Emulgen PP 150;XUS 15176;Supronic E 800;WL 440;Lupranol 2022;Pluronic F 108;Pluronic l62 (mw 2500);75-H-1400;Pluronic F 68LF;Supronic B 50;Nissan Unilube 50MB168X;Pluronic L;.alpha.-Hydro-.omega.-hydroxypoly(oxyethylene)poly(oxypropylene)po ly(oxyethylene) block copolymer;F-108;Nutek 7C;Oxirane, methyl-, polymer with oxirane, ether with 1,2-propanediol (2:1);Poly-G WT 9150;Supronic E 400;Monolan 12000E80;Teric PE;Teric PE 61;Slovanik 610;component of Casakol;Slovanik T 320;Pluronic F 88;Genapol PF;PAG;Eban 710;Pluronic L 68;Glycols, polyethylenepolypropylene;Glycols, polyethylene-polypropylene;Genapol PF 10;Synperonic PE 30/40;Oxalgon;Highflex 443;Separol WF 41;Polyoxyethylene-polyoxypropylene polymer;Oxilube 50/150;Poloxalene 2930;Pluronic L 92;Oxirane, polymer with methyloxirane;Poly(ethylene oxide-co-propylene oxide);Polyoxyethylene-polyoxypropylene;Laprol 1502;Pronon 204;Ucon 25H;TsL 431;Carpol 2050;PAG 2;Pluriol L 64;Pluronic F;Jeffox FF 200;Pluronic L 62;Pluronic L 31;Newpol 75H90000;component of Epitrate;Poloxalene;Epon 420;Slovanik M 340;Proxanol 158;Monolan PB;Poloxamer 101;Adeka CM 294;Pluronic l64 (mw 2900);Nalco SPF-WTB 33;Polypropoxylated, polyethoxylated propylene glycol;Epan U 102;Ethylene oxide-propylene oxide copolymer;60407-69-4;Polyethylene oxide-polypropylene oxide;Epan 742;Nissan Pronon 201;Laprol 1601;CF 0802;Desmophen 7100;Oxirane, methyl-, polymer with oxirane;Pluriol SC 9361;Proxanol P 168;PRO 21;Rokopol 30P9;Nissan Unilube 750DE2620;Pluronic L-101;Pluronic 10R8;Separol WF 34;Poloxalene L64;Proksanol;PLURONIC(TM) L62;“Purina Bloat Block” [Purina];“Therabloat” [Pfizer];PLURONIC L-81;POLOXALENE FREE-CHOICE LIQUID TYPE C FEED;POLOXALENE;BIS[HYDROXYETHYLPOLY(ETHYLENEOXY)ETHYLPROPYLENEGLYCOL;DIPOLYOXYETHYLATED-POLYPROPYLENEGLYCOL ETHER;POLY(OXYETHYLENE)-POLY(OXYPROPYLENE)-POLY(OXYETHYLENE) POLYMER;Polypropylene glycol ethoxylate;EO/PO block polymer;POP/POE ether;POLY(ETHYLENE GLYCOL)-BLOCK-POLY(PROPYLENE GLYCOL)-BLOCK-POLY(ETHYLENE GLYCOL) MN5800;polyether polyol;Surflo HS 1;Proxanol P 268;Slovanik T 310;Pluracol 686;Pronon 201;Nixolen SL 19;Industrol N 3;Poloxamer 182LF;Pluriol PE;Proxanol 228;Emulgen PP 250;Propylene oxide-ethylene oxide polymer;1,2-Propyleneglycol, ethoxylated and propoxylated;Nissan Unilube DE 60;Carpol 2040;Excenol 2026T;Emkalyx EP 64;Pluronic 31R2;Pluronic L-81;ZS 2185;Polyoxyethylenated poly (oxypropylene);see Oxirane,methyl-,polymers,polymer with oxirane;Teric PE70;PS 072;polyethylene-polypropylene ;;;Supronic B 75;Teric PE40;Pluronic l44;Plonon 201;Pluronic F 127;Nissan Unilube 80DE40E;Sipol L 61;Ucon 75H;M 90/20;Pluronic F87-A7850;Pluronic L 64;FT 257;Therabloat;Emkalyx L101;Epan 720;Tergitol XH (nonionic);Pluronic F 125;Breox 50A1000;Bloat Guard;Nissan Unilube 80DE40U;Poloxamer 108;MF 12 (polyether);Polyoxyethylene - polyoxypropylene copolymer;Proxanol 168;Epan U 103;Poly-G WT 90000;Pluracol V;Hydrowet;Oxirane,methyl-,polymers,polymer with oxirane;XD 8379;Poly (propylene oxide-ethylene oxide);PEG/PPG-125/30 Copolymer;Tergitol monionic XH;Nixolen;Slovanik 660;Pluronic P-75;Magcyl;Laprol 2402C;Adeka Carpol MH 150;WL 1590;Poly(oxyethylene)-poly(oxypropylene) polymer;Oxirane-methyloxirane polymer;Poloxalkol;Teric PE 62;Emkalyx L 101;Pluronic P 75;65187-10-2;Pluronic L 101;Poly(oxyethylene)-poly(oxypropylene) glycol;Pluronic P 104;BSP 5000;Newpol PE-88;Epan 740;Polypropylene glycol, ethoxylated;Propane-1,2-diol, ethoxylated, propoxylated;Niax 16-46;Poloxalene [USAN:BAN:INN];Synalox 50-50B;50MB-26X;75H380000;Unilube 50MB26X;Jeffox PPG 2000;Pluronic L 24;Epan 420;Pluriol PE 6810;Poloxamer;Slovanik M;Pluronic P-65;Synthionic 80-20;Slovanik 630;WS 661;Pronon 208;Pluronic F 68;Synperonic pe(R)/F68;

 

Polyethylene-polypropylene glycol Specification

The Polyethylene-polypropylene glycol is an organic compound with the formula HO.(C2H4O)m.(C3H6O)n.H. The IUPAC name of this chemical is 2-methyloxirane; oxirane. With the CAS registry number 9003-11-6, it is also named as 1,2-Propyleneglycol, ethoxylated and propoxylated. The product's categories are Polymers; Biological DetergentsSerum-free Media; Companion Products and Reagents; Cell Culture; Materials Science; PEG-PPG CopolymersHydrophobic Polymers; Propylene Glycol. Besides, it is , which should be stored in a closed dark and well-ventilated place. It is non-ionic surface active agent, which is used for the manufacture of polyurethane foam, adhesives and elastomers, etc. What's more, it is used as stabilizer, solubilizer and spice concentrates.Polyethylene-polypropylene glycol can be prepared by Ethylene oxide and propylene oxide.

Physical properties about Polyethylene-polypropylene glycol are: 
(1)ACD/LogP: 0.472; (2)ACD/LogD (pH 5.5): 0.47; (3)ACD/LogD (pH 7.4): 0.47; (4)ACD/BCF (pH 5.5): 1.35 ; (5)ACD/BCF (pH 7.4): 1.35; (6)ACD/KOC (pH 5.5): 43.03 ; (7)ACD/KOC (pH 7.4): 43.03; (8)#H bond acceptors: 8; (9)#Freely Rotating Bonds: 12; (10)Index of Refraction: 1.452; (11)Molar Refractivity: 69.341 cm3; (12)Molar Volume: 257.1 cm3; (13)Polarizability: 27.489 10-24cm3; (14)Surface Tension: 39.2150001525879 dyne/cm; (15)Density: 1.184 g/cm3; (16)Flash Point: 160.524 °C; (17)Enthalpy of Vaporization: 61.761 kJ/mol; (18)Boiling Point: 370.681 °C at 760 mmHg;

When you are using Polyethylene-polypropylene glycol, please be cautious about it as the following:
It is harmful in contact with skin and toxic by inhalation, in contact with skin and if swallowed. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, this chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable gloves and eye/face protection, do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) and avoid contact with skin and eyes. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: O1CC1.O1C(C)C1
(2)InChI: InChI=1/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
(3)InChIKey: RVGRUAULSDPKGF-UHFFFAOYAI
(4)Std. InChI: InChI=1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
(5)Std. InChIKey: RVGRUAULSDPKGF-UHFFFAOYSA-N

The toxicity data of Polyethylene-polypropylene glycol is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 175mg/kg (175mg/kg)   Microvascular Research. Vol. 8, Pg. 320, 1974.
mouse LD50 oral 3gm/kg (3000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 28(12), Pg. 56, 1984.
mouse LD50 oral > 15gm/kg (15000mg/kg)   Drug and Chemical Toxicology. Vol. 1, Pg. 89, 1977/1978.
mouse LD50 oral 45gm/kg (45000mg/kg)   Toxicology and Applied Pharmacology. Vol. 16, Pg. 675, 1970.
mouse LDLo intraperitoneal 5gm/kg (5000mg/kg)   Therapie. Vol. 14, Pg. 721, 1959.
mouse LDLo intravenous 6gm/kg (6000mg/kg)   Therapie. Vol. 14, Pg. 721, 1959.
mouse LDLo oral 15gm/kg (15000mg/kg)   Therapie. Vol. 14, Pg. 721, 1959.
rabbit LD50 oral 35gm/kg (35000mg/kg)   Toxicology and Applied Pharmacology. Vol. 16, Pg. 675, 1970.
rat LC50 inhalation 320mg/m3/4H (320mg/m3) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: OTHER CHANGES

LIVER: OTHER CHANGES
National Technical Information Service. Vol. OTS0539401,
rat LD50 oral 5700mg/kg (5700mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 28(12), Pg. 56, 1984.
rat LDLo intraperitoneal 10gm/kg (10000mg/kg)   Therapie. Vol. 14, Pg. 721, 1959.
rat LDLo oral 16gm/kg (16000mg/kg)   Toxicology and Applied Pharmacology. Vol. 16, Pg. 675, 1970.

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