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Basic information

  • Name:
  • Potassium gluconate

  • CAS No.:
  • 299-27-4

  • Molecular Structure:
  • Formula:
  • C6H11O7K
  • Molecular Weight:
  • 234.25
  • Deleted CAS:
  • 8059-85-6
  • Synonyms:
  • D-Gluconicacid, monopotassium salt (9CI);Gluconic acid, monopotassium salt, D- (8CI);Gluconic acid potassium salt;Gluconsan K;Helshas K;K-IAO;Kalimozan;Kalium-Beta;Kaon;Katorin;Katrin;Potalium;Potasoral;Potassium D-gluconate;Potassuril;Sirokal;Tumil K;
  • EINECS:
  • 206-074-2
  • Melting Point:
  • 183 °C (dec.)(lit.)
  • Boiling Point:
  • 673.6 °C at 760 mmHg
  • Flash Point:
  • 375.2 °C
  • Appearance:
  • white to off-white crystalline or granular powder
  • Risk Codes:
  • 36/37/38
  • Safety Description:
  • 24/25 Details

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Chemistry


IUPAC Name: Potassium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate 
Empirical Formula: C6H11KO7
Molecular Weight: 234.2456
Canonical SMILES: C(C(C(C(C(C(=O)[O-])O)O)O)O)O.[K+]
Isomeric SMILES: C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.[K+]
InChI: InChI=1S/C6H12O7.K/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1
InChIKey: HLCFGWHYROZGBI-JJKGCWMISA-M
EINECS: 206-074-2
Melting Point: 183 °C (dec.)(lit.)
Flash Point: 375.2 °C
Enthalpy of Vaporization: 113.2 kJ/mol
Boiling Point: 673.6 °C at 760 mmHg
Vapour Pressure: 4.95E-21 mmHg at 25 °C
Product Categories: Biochemistry; Glucose; Sugar Acids; Sugars
Classification Code of Potassium gluconate (CAS NO.299-27-4): Drug / Therapeutic Agent; Replenisher [electrolyte] 

Uses

 Potassium gluconate (CAS NO.299-27-4) can be used as a medicinal and potassium supplement agent.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 2333mg/kg (2333mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 6, Pg. 810, 1972.
mouse LD50 oral 9100mg/kg (9100mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: SLEEP

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Kiso to Rinsho. Clinical Report. Vol. 6, Pg. 810, 1972.
mouse LD50 subcutaneous 8190mg/kg (8190mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 6, Pg. 810, 1972.
rat LD50 intraperitoneal 2664mg/kg (2664mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 6, Pg. 810, 1972.
rat LD50 oral 10380mg/kg (10380mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: SLEEP

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Kiso to Rinsho. Clinical Report. Vol. 6, Pg. 810, 1972.
rat LD50 subcutaneous 9650mg/kg (9650mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 6, Pg. 810, 1972.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Risk Statements : 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements : 24/25
S24/25:Avoid contact with skin and eyes.
WGK Germany : 1
RTECS : LZ5230000
Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. When heated to decomposition it emits toxic fumes of K2O.

Specification

  Potassium gluconate (CAS NO.299-27-4), its Synonyms are D-Gluconic acid, monopotassium salt ; Gluconic acid potassium salt ; Gluconic acid, monopotassium salt ; Gluconsan K ; K-Iao ; KOK ; Kalium Gluconate ; Kalium-beta ; Kaon ; Kaon elixir ; Katorin ; Monopotassium D-gluconate ; Potalium ; Potasoral ; Potassium D-gluconate . It is white to off-white crystalline or granular powder.

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