Povidone (9003-39-8),Povidone (9003-39-8) Manufacturers & Suppliers,Synthesis,MSDS

Basic information

Name:
Povidone
Superlist Name:
Polyvinylpyrrolidone
CAS No.:
9003-39-8
Molecular Structure:
Formula:
C₆H₉NO
Molecular Weight:
111.1418
Synonyms:
2-Pyrrolidinone,1-vinyl-, polymers (8CI);1-Vinyl-2-pyrrolidinone polymer;1-Vinyl-2-pyrrolidone homopolymer;1-Vinyl-2-pyrrolidone polymer;143RP;40K;40K (vinyl polymer);ACP 10;AT 717;Agent AT 717;Agrimer 15;Agrimer 30;Agrimer 90;Agrimer K 30;Albigen A;Aldacol Q;Antaron P 804;Antitox Vana;B7509;Bolinan;Cevian A 88036;Deltaspeed AF;Discol K 30L;Disintex 200;Divergan EF;Divergan F;Divergan RS;Epocros WS 560;Gaftex AE-K 15;Ganex P 804;Hemodesis;Hemodez;K115;K 115 (vinyl polymer);K 12;K 120;K 15;K 15 (polymer);K 17;K 25;K 25(surfactant);K 27/32;K 29-32;K 30;K 30C;K 30G;K 30PH;K 30W;K 50;K 50 (vinyl polymer);K 60;K 60 (polymer);K 85;K 85(vinyl polymer);K 90;K 90W;K 92;K 92 (vinyl polymer);Kollidon;Kollidon12PF;Kollidon 17;Kollidon 17PF;Kollidon 25;Kollidon 30;Kollidon 90;Kollidon 90F;KollidonCE 50/50;Kollidon K 15;Kollidon K 17;Kollidon K 25;Kollidon K 29/32;Kollidon K 30;Kollidon K 60;Kollidon K 90;Kollidon K 90F;Konkrepol AD 1;Konkrepol B;LFC;Lumiten PPR 8450;Lumiten PR 8450;Luvicross M;Luviskol K;Luviskol K 12;Luviskol K 120;Luviskol K 17;Luviskol K 17F;Luviskol K 25;Luviskol K 30;Luviskol K 30SP;Luviskol K 60;Luviskol K 80;Luviskol K 85CQ;Luviskol K 90;Luviskol K 90L;Luviskol K 910;Luviskol KPO;Luvitec K15;Luvitec K 17;Luvitec K 30;Luvitec K 60;Luvitec K 90;Luvitec K 90PH;MPK90;MRTU 8457-79;N-Vinyl-2-pyrrolidinone homopolymer;N-Vinyl-2-pyrrolidonehomopolymer;N-Vinyl-2-pyrrolidone polymer;N-Vinylbutyrolactam polymer;N-Vinylpyrrolidinone polymer;N-Vinylpyrrolidone homopolymer;N-Vinylpyrrolidone polymer;NP-K 30;NPK 15;NPK 90;Neocompensan;Neohemodes;P 0696;P-XL;PAK-K 15;PK 771;PV 03;PV 03 (vinyl pyrrolidone polymer);PV05;PVK 30;PVP;PVP 10;PVP 1230;PVP 18;PVP 25;PVP 3000;PVP 360;PVP 40;PVP 4000;PVP 50;PVP 99;PVP-K;PVP-K 12;PVP-K 120;PVP-K 15;PVP-K 17;PVP-K25;PVP-K 26/28;PVP-K 3;PVP-K 30;PVP-K 40;PVP-K 60;PVP-K 70;PVP-K 80;PVP-K 90;PVP-K 90K95;PVPP;Povidone/Polyvinylpyrrolidone(PVP);Polyvinylpyrrolidone;Povidone K-30;
Density:
1.144g/cm³
Boiling Point:
217.6 °C at 760 mmHg
Flash Point:
93.9 °C
Solubility:
10g/100mL at 2 °C
Safety Description:
S22; S24/25 Details

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Chemistry

Molecular Structure of Povidone (CAS NO.9003-39-8):

IUPAC Name: 1-ethenylpyrrolidin-2-one
Empirical Formula: C₆H₉NO
Molecular Weight: 111.1418
H bond acceptors: 2
H bond donors: 0
Freely Rotating Bonds: 1
Polar Surface Area: 20.31 Å²
Index of Refraction: 1.593
Molar Refractivity: 32.92 cm³
Molar Volume: 97.1 cm³
Surface Tension: 52.3 dyne/cm
Density: 1.144 g/cm³
Flash Point: 93.9 °C
Enthalpy of Vaporization: 45.39 kJ/mol
Boiling Point: 217.6 °C at 760 mmHg
Vapour Pressure: 0.132 mmHg at 25°C
Smiles
N1(C(CCC1)=O)[C@@H](C*)*
Classification Code: Blood Substitutes; Hematologic Agents; Pharmaceutic aids; Plasma substitutes; Radioactive agent; Tumor data

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	100gm/kg (100000mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 486, 1974.
mouse	LD50	intraperitoneal	12gm/kg (12000mg/kg)		FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 486, 1974.
mouse	LD50	oral	> 40gm/kg (40000mg/kg)		FAO Nutrition Meetings Report Series. Vol. 40, Pg. 164, 1967.
mouse	LD50	unreported	16gm/kg (16000mg/kg)		Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. Vol. 19, Pg. 212, 1985.
mouse	LDLo	oral	3gm/kg (3000mg/kg)		Biomaterials, Medical Devices, and Artificial Organs. Vol. 12, Pg. 1, 1984.
mouse	LDLo	oral	3gm/kg (3000mg/kg)		Biomaterials, Medical Devices, and Artificial Organs. Vol. 12, Pg. 1, 1984.
mouse	LDLo	oral	5gm/kg (5000mg/kg)		Biomaterials, Medical Devices, and Artificial Organs. Vol. 12, Pg. 1, 1984.
rabbit	LD50	oral	1040mg/kg (1040mg/kg)		Veterinariya. Veterinary Science. Vol. 61(12), Pg. 68, 1985.
rat	LD50	oral	100gm/kg (100000mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 486, 1974.

Consensus Reports

IARC Cancer Review: Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 19 ,1979,p. 461.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

Safety Profile

Suspected carcinogen with experimental neoplastigenic data. When heated to decomposition it emits toxic fumes of NO_x.
The Safety Statements information of Povidone (CAS NO.9003-39-8):
22: Do not breathe dust
24/25: Avoid contact with skin and eyes
WGK Germany: 1
RTECS: TR8370000
HS Code: 39059990

Specification

Povidone , with CAS number of 9003-39-8, can be called Povidone/Polyvinylpyrrolidone(PVP) ; PVP 3000 ; N-Vinylpyrrolidone polymer ; N-Vinylbutyrolactam polymer ; N-Vinylpyrrolidone homopolymer ; N-Vinyl-2-pyrrolidone polymer ; N-Vinyl-2-pyrrolidinone homopolymer .