Basic information
- Name:
Benzamide,4-amino-N-[2-(diethylamino)ethyl]-, hydrochloride (1:1)
- Superlist Name:
- Procainamide hydrochloride
- CAS No.:
614-39-1
- Molecular Structure:
![Molecular Structure of 614-39-1 (Benzamide,4-amino-N-[2-(diethylamino)ethyl]-, hydrochloride (1:1))](http://www.lookchem.com/300w/2010/0623/614-39-1.jpg)
- Formula:
- C13H22ClN3O
- Molecular Weight:
- 271.83
- Synonyms:
- Procamid;Procamide;Procan SR;Procapan;Procardyl;Pronestyl;Pronestyl hydrochloride;Spicain amide;Benzamide,4-amino-N-[2-(diethylamino)ethyl]-, monohydrochloride (9CI);Benzamide, p-amino-N-[2-(diethylamino)ethyl]-,monohydrochloride (8CI);4-Amino-N-[2-(diethylamino)ethyl]benzamidemonohydrochloride;Amidoprocaine;Amisalin;Cardiorytmin;HC 5006;Novocaineamide hydrochloride;Novocamid hydrochloride;Procainamidemonohydrochloride;
- EINECS:
- 210-381-7
- Melting Point:
- 165-168 °C
- Boiling Point:
- 421.8 °C at 760 mmHg
- Flash Point:
- 208.9 °C
- Solubility:
- soluble in water
- Appearance:
- White to slightly yellow powder
- Hazard Symbols:
Xn- Risk Codes:
- 22-36/37/38
- Safety Description:
- 26-36-37/39 Details
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Chemistry
Molecular Formula: C13H22ClN3O 
Formula Weight: 271.79
Melting point: 165-168 °C
Flash Point: 208.9 °C
Boiling Point: 421.8 °C at 760 mmHg
Water Solubility : PROCAINAMIDE HYDROCHLORIDE (614-39-1) is soluble
Vapour Pressure: 2.54E-07 mmHg at 25°C
Sensitive : Light Sensitive/Air Sensitive
Appearance of PROCAINAMIDE HYDROCHLORIDE (614-39-1): Solid
Formula Weight: 271.79
Melting point: 165-168 °C
Flash Point: 208.9 °C
Boiling Point: 421.8 °C at 760 mmHg
Water Solubility : PROCAINAMIDE HYDROCHLORIDE (614-39-1) is soluble
Vapour Pressure: 2.54E-07 mmHg at 25°C
Sensitive : Light Sensitive/Air Sensitive
Appearance of PROCAINAMIDE HYDROCHLORIDE (614-39-1): Solid
Toxicity Data With Reference
| 1. | orl-man LDLo:857 mg/kg/60D-I:BLD | AHJOA2 American Heart Journal. 105 (1983),1035. | ||
| 2. | orl-man TDLo:200 mg/kg/4W-I:BLD | AIMDAP Archives of Internal Medicine. 145 (1985),700. | ||
| 3. | orl-man TDLo:2786 mg/kg/56W-I:BLD,MSK | AJMEAZ American Journal of Medicine. 80 (1986),999. | ||
| 4. | ivn-rat LD50:95 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 18 (1968),1127. | ||
| 5. | orl-mus LD50:1110 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 18 (1968),1127. | ||
| 6. | ipr-mus LD50:325 mg/kg | APTOA6 Acta Pharmacologica et Toxicologica. 28 (1970),17. | ||
| 7. | scu-mus LD50:800 mg/kg | PSEBAA Proceedings of the Society for Experimental Biology and Medicine. 73 (1950),236. | ||
| 8. | ivn-mus LD50:94,640 µg/kg | NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),719. | ||
| 9. | ims-mus LD50:860 mg/kg | THERAP Therapie. 9 (1954),332. | ||
| 10. | ivn-mus LD50:150 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 18 (1968),112 |
Safety Profile
Hazard Codes : Xn: Harmful
Risk Statements : 22: Harmful if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements : 26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37/39: Wear suitable gloves and eye/face protection
WGK Germany : 3
RTECS : CV2295000
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects by ingestion: agranulocytosis, thrombocytopenia, leukopenia, joint effects. Used as a local anesthetic. When heated to decomposition PROCAINAMIDE HYDROCHLORIDE (614-39-1) emits very toxic fumes of HCl and NOx.
Risk Statements : 22: Harmful if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements : 26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37/39: Wear suitable gloves and eye/face protection
WGK Germany : 3
RTECS : CV2295000
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects by ingestion: agranulocytosis, thrombocytopenia, leukopenia, joint effects. Used as a local anesthetic. When heated to decomposition PROCAINAMIDE HYDROCHLORIDE (614-39-1) emits very toxic fumes of HCl and NOx.
Specification
Storage of PROCAINAMIDE HYDROCHLORIDE (614-39-1): Keep container tightly closed. Keep container dry. Keep in a cool place. Keep in a cool, well-ventilated place. Ground all equipment containing material. Combustible materials should be stored away from extreme heat and away from strong oxidizing agents.