Pritelivir

Base Information

• Chemical Name: Pritelivir
• CAS No.: 348086-71-5
• Molecular Formula: C18H18N4O3S2
• Molecular Weight: 402.49100
• UNII: 07HQ1TJ4JE
• DSSTox Substance ID: DTXSID70188344
• Nikkaji Number: J1.735.177J
• Wikipedia: Pritelivir
• Wikidata: Q15410303
• NCI Thesaurus Code: C136516
• Pharos Ligand ID: 9NMJFSHA3SNV
• Metabolomics Workbench ID: 144588
• ChEMBL ID: CHEMBL4069597
• Mol file: 348086-71-5.mol

Synonyms:AIC316;BAY 57-1293;N-(5-(aminiosulfonyl)-4-methyl-1,3-thiazol-2-yl)-N-methyl-2-(4-(2-pyridinyl)phenyl)acetamide;pritelivir

Chemical Property of Pritelivir

Chemical Property:

• Boiling Point: 639.4±65.0 °C(Predicted)
• PKA: 9.31±0.60(Predicted)
• PSA: 142.87000
• Density: 1.396±0.06 g/cm3(Predicted)
• LogP: 4.14750
• Storage Temp.: 2-8°C(protect from light)
• Solubility.: insoluble in H2O; insoluble in EtOH; ≥13.9 mg/mL in DMSO
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 402.08203280
• Heavy Atom Count: 27
• Complexity: 617

Purity/Quality:

98%,99%, ^*data from raw suppliers

BAY57-1293 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(SC(=N1)N(C)C(=O)CC2=CC=C(C=C2)C3=CC=CC=N3)S(=O)(=O)N
• Recent ClinicalTrials: Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised Subjects
• Recent EU Clinical Trials: A randomized, open-label, multi-center, comparative trial, to assess the efficacy and safety of pritelivir versus foscarnet for the treatment of acyclovir-resistant mucocutaneous HSV infections in immunocompromised subjects (PRIOH-1)
• Uses: BAY 57-1293 is a potent inhibitor of herpes simplex virus (HSV) that target the virus helicase primase complex.