2-Anilinobenzoic acid methyl ester

Base Information

• Chemical Name: 2-Anilinobenzoic acid methyl ester
• CAS No.: 35708-19-1
• Molecular Formula: C14H13NO2
• Molecular Weight: 227.263
• Hs Code.: 2922499990
• Mol file: 35708-19-1.mol

Synonyms:methyl ester of N-phenylanthranilic acid;N-Phenyl-anthranilsaeure-methylester;o-Diphenylaminecarboxylic acid methyl ester;methyl N-phenylanthranilate;methyl 2-phenylaminobenzoate;N-phenylanthranilic acid methyl ester;2-Anilinobenzoic acid methyl ester;

Chemical Property of 2-Anilinobenzoic acid methyl ester

Chemical Property:

• Melting Point: 58-59 °C
• Boiling Point: 140 °C(Press: 0.1 Torr)
• PKA: -1.27±0.20(Predicted)
• PSA: 38.33000
• Density: 1.175±0.06 g/cm3(Predicted)
• LogP: 3.28980
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

98% ^*data from raw suppliers

METHYL-2-(PHENYLAMINO)BENZOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Anilinobenzoic acid methyl ester

There total 16 articles about 2-Anilinobenzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methyl 2-(trifluoromethylsulfonyloxy)benzoate (17763-70-1) + aniline (62-53-3) → Methyl N-phenylanthranilate (35708-19-1)

Guidance literature:

With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; at 120 ℃; Inert atmosphere;

DOI:10.1016/j.bmcl.2011.01.010

Reference yield: 99.0%

→ Methyl N-phenylanthranilate (35708-19-1)

Guidance literature:

With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; at 120 ℃;

Reference yield: 94.0%

2-(phenylamino)benzoic acid (91-40-7) + dimethyl sulfate (77-78-1) → Methyl N-phenylanthranilate (35708-19-1)

Guidance literature:

With potassium carbonate; In acetone; for 2h; Reflux;

upstream raw materials:

methanol

2-(phenylamino)benzoic acid

dimethyl sulfate

3-phenyl-1,2,3-benzotriazin-4(3H)-one

Downstream raw materials:

2-<(2-Acetylphenyl)phenylamino>benzoesaeure-methylester

2-<(2-Benzoylphenyl)phenylamino>benzoesaeure-methylester

N-(4-methoxyphenyl)-2-(phenylamino)benzamide

10-phenylacridin-9(10H)-one

Refernces

• 1、 Zhang, Qisheng,Kuwabara, Hirokazu,Potscavage, William J.,Huang, Shuping,Hatae, Yasuhiro,Shibata, Takumi,Adachi, Chihaya. "Anthraquinone-based intramolecular charge-transfer compounds: Computational molecular design, thermally activated delayed fluorescence, and highly efficient red electroluminescence". . p. 18070 - 18081. Retrieved 2014.
• 2、 -. "Thermally-activated delayed fluorescence material and preparation method and application thereof". Paragraph 0017; 0037-0040. . Retrieved 2020/11/12.
• 3、 Deckers, Jasper,Cardeynaels, Tom,Penxten, Huguette,Ethirajan, Anitha,Ameloot, Marcel,Kruk, Mikalai,Champagne, Beno?t,Maes, Wouter. "Near-Infrared BODIPY-Acridine Dyads Acting as Heavy-Atom-Free Dual-Functioning Photosensitizers". supporting information. p. 15212 - 15225. Retrieved 2020/10/19.