3,3-Dibromo-2-oxo-1,1,1-trifluorobutane

Base Information

• Chemical Name: 3,3-Dibromo-2-oxo-1,1,1-trifluorobutane
• CAS No.: 382-12-7
• Molecular Formula: C4H3Br2F3O
• Molecular Weight: 283.86900
• Hs Code.: 2914700090
• Mol file: 382-12-7.mol

Synonyms:3,3-dibromo-1,1,1-trifluoro-2-butanone;3,3-Dibrom-1,1,1-trifluor-butan-2-on;3,3-Dibromo-2-oxo-1,1,1-trifluorobutane;3,3-dibromo-1,1,1-trifluoro-butan-2-one;2-Butanone,3,3-dibromo-1,1,1-trifluoro;3,3-dibromo-1,1,1-trifluorobutanone;

Chemical Property of 3,3-Dibromo-2-oxo-1,1,1-trifluorobutane

Chemical Property:

• Boiling Point: 124 °C
• PSA: 17.07000
• Density: 2?+-.0.06 g/cm3(Predicted)
• LogP: 2.62380

Purity/Quality:

97% ^*data from raw suppliers

3,3-Dibromo-1,1,1-trifluorobutan-2-one 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,3-Dibromo-2-oxo-1,1,1-trifluorobutane

There total 2 articles about 3,3-Dibromo-2-oxo-1,1,1-trifluorobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1,1,1-trifluoro-2-butanone (381-88-4) → 3,3-dibromo-1,1,1-trifluoro-2-butanone (382-12-7)

Guidance literature:

With N-Bromosuccinimide; Perbenzoic acid; In tetrachloromethane; for 36h; Heating; Irradiation;

DOI:10.1021/jo00047a015

Reference yield:

3-bromo-1,1,1-trifluoro-2-butanone (382-01-4) → 3,3-dibromo-1,1,1-trifluoro-2-butanone (382-12-7)

Guidance literature:

With bromine; sodium acetate; acetic acid;

Reference yield:

3,3-dibromo-1,1,1-trifluoro-2-butanone (382-12-7) + 4-chloro-2-fluoro-5-hydroxyphenylhydrazine (91167-74-7) → 3,3,3-trifluoro-2-oxopropanal 1-(4-chloro-2-fluoro-5-hydroxyphenylhydrazone) (188490-63-3)

Guidance literature:

3,3-dibromo-1,1,1-trifluoro-2-butanone; With sodium acetate; In water; at 80 ℃; for 1h; Cooling with ice;

4-chloro-2-fluoro-5-hydroxyphenylhydrazine; In water; at 0 - 20 ℃; for 2h;

upstream raw materials:

1,1,1-trifluoro-2-butanone

3-bromo-1,1,1-trifluoro-2-butanone

Downstream raw materials:

6,7-dichloro-2-(trifluoromethyl)-3-methylquinoxaline

1,1,1-trifluoro-2,3-butanedione

3,3,3-trifluoro-2-oxopropanal 1-(4-chloro-2-fluoro-5-hydroxyphenylhydrazone)

Refernces

• 1、 -. "Pyridazin-3-one derivatives, their use, and intermediates for their production". Page column 55-56. . Retrieved 2010/01/30.
• 2、 Cushman, Mark,Patel, Hemantkumar H.,Scheuring, Johannes,Bacher, Adelbert. "19F NMR Studies on the Mechanism of Riboflavin Synthase. Synthesis of 6-(Trifluoromethyl)-7-oxo-8-(D-ribityl)lumazine and 6-(trifluoromethyl)-7-methyl-8-(D-ribityl)lumazine". . p. 5630 - 5643. Retrieved 2007/10/02.