Benzenesulfonic acid, 4-nitro-, phenylmethyl ester

Base Information

• Chemical Name: Benzenesulfonic acid, 4-nitro-, phenylmethyl ester
• CAS No.: 4028-53-9
• Molecular Formula: C₁₃H₁₁NO₅S
• Molecular Weight: 293.3
• Mol file: 4028-53-9.mol

Synonyms:

Chemical Property of Benzenesulfonic acid, 4-nitro-, phenylmethyl ester

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenesulfonic acid, 4-nitro-, phenylmethyl ester

There total 2 articles about Benzenesulfonic acid, 4-nitro-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Nitrobenzenesulfonyl chloride (98-74-8) + benzyl alcohol (100-51-6,185532-71-2) → benzyl p-nitrobenzenesulphonate (4028-53-9)

Guidance literature:

With sodium hydride; Multistep reaction; 1.) THF, 10 min, 2.) THF;

DOI:10.1021/ja00099a015

Reference yield:

p-nitrobenzenesulfonic acid (138-42-1) + benzyl bromide (100-39-0) → benzyl p-nitrobenzenesulphonate (4028-53-9)

Guidance literature:

Multistep reaction; 1.) Emmons procedure, 2.) acetonitrile, 50 deg C, 5 h;

Reference yield:

benzyl p-nitrobenzenesulphonate (4028-53-9) + 4-methoxy-aniline (104-94-9) → benzyl(4-methoxyphenyl)amine (17377-95-6)

Guidance literature:

In acetonitrile; at 30 ℃; Rate constant; secondary kinetic isotope effect;

upstream raw materials:

p-nitrobenzenesulfonic acid

benzyl bromide

4-Nitrobenzenesulfonyl chloride

benzyl alcohol

Downstream raw materials:

benzyl(4-methoxyphenyl)amine

N-(4-methoxybenzyl)aniline

p-nitrobenzenesulfonate anion

4-methoxyanilinium⁽¹⁺⁾

Refernces

• 1、 Yoh, Soo-Dong,Tsuno, Yuho,Fujio, Mizue,Sawada, Masami,Yukawa, Yasuhide. "Multiple Structure-Reactivity Relationships for a Menschutkin-type SN2 Reaction". . p. 7 - 14. Retrieved 2007/10/02.