Phenol, 4-(1,1-dimethylethyl)-2,6-bis(methoxymethyl)-

Base Information

• Chemical Name: Phenol, 4-(1,1-dimethylethyl)-2,6-bis(methoxymethyl)-
• CAS No.: 421546-91-0
• Molecular Formula: C14H22O3
• Molecular Weight: 238.32300
• Hs Code.: 2909500000
• Mol file: 421546-91-0.mol

Synonyms:2,6-Bis(methoxymethyl)-4-tert-butylphenol;4-(tert-Butyl)-2,6-bis(methoxymethyl)phenol;Phenol,4-(1,1-dimethylethyl)-2,6-bis(methoxymethyl);

Chemical Property of Phenol, 4-(1,1-dimethylethyl)-2,6-bis(methoxymethyl)-

Chemical Property:

• PSA: 38.69000
• LogP: 2.98250

Purity/Quality:

99% ^*data from raw suppliers

4-(tert-Butyl)-2,6-bis(methoxymethyl)phenol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenol, 4-(1,1-dimethylethyl)-2,6-bis(methoxymethyl)-

There total 1 articles about Phenol, 4-(1,1-dimethylethyl)-2,6-bis(methoxymethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + O-acetyl-2,6-bis(acetoxymethyl)-para-tert-butylphenol → 2,6-bis(methoxymethyl)-para-tert-butylphenol (421546-91-0)

Guidance literature:

With toluene-4-sulfonic acid; at 120 ℃; for 0.5h; Microwave irradiation;

DOI:10.1039/b813789g

Reference yield:

2,6-bis(methoxymethyl)-para-tert-butylphenol (421546-91-0) + 1,1,2,2,3,3-hexafluoropropane-1,3-disulfonyl difluoride (82727-16-0) → C17H21F7O7S2

Guidance literature:

2,6-bis(methoxymethyl)-para-tert-butylphenol; With triethylamine; In tetrahydrofuran; at 0 ℃;

1,1,2,2,3,3-hexafluoropropane-1,3-disulfonyl difluoride; In tetrahydrofuran; at 0 ℃; for 8h;

Reference yield:

2,6-bis(methoxymethyl)-para-tert-butylphenol (421546-91-0) → C17H21F6O8S2(1-)*Na(1+)

Guidance literature:

Multi-step reaction with 2 steps

1.1: triethylamine / tetrahydrofuran / 0 °C

1.2: 8 h / 0 °C

2.1: sodium hydroxide / tetrahydrofuran; methanol / 20 °C

With triethylamine; sodium hydroxide; In tetrahydrofuran; methanol;

upstream raw materials:

methanol

Refernces