2-Propenethioic acid, 3-phenyl-, S-ethyl ester

Base Information

• Chemical Name: 2-Propenethioic acid, 3-phenyl-, S-ethyl ester
• CAS No.: 42893-53-8
• Molecular Formula: C11H12OS
• Molecular Weight: 192.282
• Mol file: 42893-53-8.mol

Synonyms:

Chemical Property of 2-Propenethioic acid, 3-phenyl-, S-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propenethioic acid, 3-phenyl-, S-ethyl ester

There total 6 articles about 2-Propenethioic acid, 3-phenyl-, S-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Cinnamic acid (621-82-9) + ethanethiol (75-08-1) → S-ethyl thiocinnamate (42893-53-8)

Guidance literature:

With polyphosphate ester; at 20 ℃;

DOI:10.1016/j.ejmech.2011.09.008

Reference yield: 90.9%

2-Methanesulfinyl-3-phenyl-thiopropionic acid S-ethyl ester (133017-15-9) → S-ethyl thiocinnamate (42893-53-8)

Guidance literature:

at 120 ℃; for 1h; under 150 Torr;

Reference yield: 65.0%

ethanol (64-17-5) + Cinnamic acid (621-82-9) → S-ethyl thiocinnamate (42893-53-8)

Guidance literature:

With N-Bromosuccinimide; benzyltriethylammonium tetrathiomolybdate; triphenylphosphine; In chloroform; at 28 ℃; for 4h;

DOI:10.1002/ejoc.200900956

upstream raw materials:

ethyl 3-phenyl-2-propenoate

(ethylthio)trimethylsilane

2-Methanesulfinyl-3-phenyl-thiopropionic acid S-ethyl ester

benzyl bromide

Downstream raw materials:

S-ethyl 3-phenylpropionic acid thioester

(E)-3-Phenyl-acrylic acid 1-methyl-3-phenyl-propyl ester

3-phenylpropyl cinnamate

Refernces

• 1、 Li, Ninglin,Ou, Jun,Miesch, Michel,Chiu, Pauline. "Conjugate reduction and reductive aldol cyclization of α,β- unsaturated thioesters catalyzed by (BDP)CuH". supporting information; experimental part. p. 6143 - 6147. Retrieved 2011/10/08.
• 2、 Van Zijl, Anthoni W.,Szymanski, Wiktor,Lopez, Ferrnando,Minnaard, Adriaan J.,Feringa, Ben L.. "Catalytic enantioselective synthesis of vicinal dialkyl arrays". supporting information; experimental part. p. 6994 - 7002. Retrieved 2009/05/09.