2,4,6-Tribromobenzaldehyde

Base Information

• Chemical Name: 2,4,6-Tribromobenzaldehyde
• CAS No.: 45859-98-1
• Molecular Formula: C7H3Br3O
• Molecular Weight: 342.812
• Mol file: 45859-98-1.mol

Synonyms:2,4,6-tribromobenzeneamine;2,4,6-Tribromobenzenamine;2,4,6-tribromo-benzaldehyde;Benzenamine,2,4,6-tribromo;Aniline,2,4,6-tribromo;sym-Tribromoaniline;2,4,6-Tribrom-benzaldehyd;Aniline tribromide;s-Tribromoaniline;2,4,6-tribromo-aniline;2,4,6-Tribromophenylamine;2,4,6-tribromaniline;

Chemical Property of 2,4,6-Tribromobenzaldehyde

Chemical Property:

• Melting Point: 99 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 329.6±42.0 °C(Predicted)
• PSA: 17.07000
• Density: 2.290±0.06 g/cm3(Predicted)
• LogP: 3.78660
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

2,4,6-Tribromobenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4,6-Tribromobenzaldehyde

There total 9 articles about 2,4,6-Tribromobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

1,3,5-trisbromobenzene (626-39-1) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 2,4,6-tribromobenzaldehyde (45859-98-1)

Guidance literature:

1,3,5-trisbromobenzene; With lithium diisopropyl amide; In tetrahydrofuran; at -75 - -70 ℃; for 0.5h;

N,N-dimethyl-formamide; In tetrahydrofuran; at -70 ℃;

With sulfuric acid; In tetrahydrofuran; water;

DOI:10.1021/jo0340511

Reference yield:

aqueous triethylamine-N-oxide + 2,4,6-tribromo-1-(bromomethyl)benzene (54459-64-2) + 1,2-dichloro-ethane (107-06-2,52399-93-6) → 2,4,6-tribromobenzaldehyde (45859-98-1)

Guidance literature:

In water; isopropyl alcohol;

Reference yield:

2,4,6-tribromotoluene (6320-40-7) → 2,4,6-tribromobenzaldehyde (45859-98-1)

Guidance literature:

With bromine; at 200 ℃; unter der Einwirkung von Gluehlampenlicht und anschliessend Behandeln mit rauchender Schwefelsaeure bei 100grad;

upstream raw materials:

2,4,6-tribromotoluene

3-amino-2,4,6-tribromo-benzaldehyde

2,4,6-Tribrombenzylalkohol

1,3,5-trisbromobenzene

Downstream raw materials:

1-(2,4,6-tribromo-phenyl)-ethanol

N¹,N¹-Diethyl-N⁴-{2-[(E)-2-(2,4,6-tribromo-phenyl)-vinyl]-quinazolin-4-yl}-pentane-1,4-diamine

N⁴-{7-Chloro-2-[(E)-2-(2,4,6-tribromo-phenyl)-vinyl]-quinazolin-4-yl}-N¹,N¹-diethyl-pentane-1,4-diamine

formic acid

Refernces

• 1、 Farrar,Sienkowska,Kaszynski. "Synthesis of 1,3,6,8-tetrabromophenanthrene via a stoichiometric Ullmann reaction". . p. 4039 - 4045. Retrieved 2007/10/03.
• 2、 -. "Method of preparing substituted benzaldehydes". . . Retrieved 2008/06/13.