3-methoxy-5,5-dimethylcyclohex-2-en-1-one

Base Information

• Chemical Name: 3-methoxy-5,5-dimethylcyclohex-2-en-1-one
• CAS No.: 4683-45-8
• Molecular Formula: C9H14O2
• Molecular Weight: 154.209
• Mol file: 4683-45-8.mol

Synonyms:

Chemical Property of 3-methoxy-5,5-dimethylcyclohex-2-en-1-one

Chemical Property:

• Vapor Pressure: 0.0394mmHg at 25°C
• Boiling Point: 239.8°C at 760 mmHg
• Flash Point: 97.2°C
• Density: 0.98g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-methoxy-5,5-dimethylcyclohex-2-en-1-one

There total 16 articles about 3-methoxy-5,5-dimethylcyclohex-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methanol (67-56-1) + dimedone (126-81-8) → 3-methoxy-5,5-dimethyl-cyclohex-2-enone (4683-45-8)

Guidance literature:

With Amberlyst-15; at 80 ℃; for 0.0766667h; under 2475.25 Torr; Flow reactor;

DOI:10.1021/acs.oprd.9b00067

Reference yield: 96.0%

methanol (67-56-1) + 3-ethoxy-5,5-dimethyl-2-cyclohexen-1-one (6267-39-6) → 3-methoxy-5,5-dimethyl-cyclohex-2-enone (4683-45-8)

Guidance literature:

With toluene-4-sulfonic acid; for 2h; Reflux;

DOI:10.1134/S1070428009110268

Reference yield: 59.0%

methanol (67-56-1) + dimedone (3471-13-4) → 3-methoxy-5,5-dimethyl-cyclohex-2-enone (4683-45-8)

Guidance literature:

With chloro-trimethyl-silane; at 20 ℃; for 24h;

DOI:10.1007/BF00961389

upstream raw materials:

diazomethane

dimedone

methanol

dimedone

Downstream raw materials:

5-Dimethoxymethyl-3,3-dimethyl-cyclohexanone

5,5-dimethyl-3-(4-trimethylsilylbut-3-ynyl)cyclohex-2-enone

6-acetoxy-5,5-dimethyl-3-methoxy-2-cyclohexenone

5,5-dimethyl-3-cyclohex-2-en-1-one

Refernces

• 1、 Mohanta, Nirmala,Chaudhari, Moreshwar B.,Digrawal, Naveen Kumar,Gnanaprakasam, Boopathy. "Rapid and Multigram Synthesis of Vinylogous Esters under Continuous Flow: An Access to Transetherification and Reverse Reaction of Vinylogous Esters". . p. 1034 - 1045. Retrieved 2019/05/24.
• 2、 Li, Pei-He,Li, Bao-Le,Hu, Hai-Chuan,Zhao, Xiao-Na,Zhang, Zhan-Hui. "Ionic liquid supported on magnetic nanoparticles as highly efficient and recyclable catalyst for the synthesis of β-keto enol ethers". . p. 118 - 122. Retrieved 2014/01/17.