22-Hydroxydocosanoic acid

Base Information

• Chemical Name: 22-Hydroxydocosanoic acid
• CAS No.: 506-45-6
• Molecular Formula: C22H44O3
• Molecular Weight: 356.59
• DSSTox Substance ID: DTXSID40415255
• Nikkaji Number: J297.196H
• Wikidata: Q27145882
• Metabolomics Workbench ID: 1337
• Mol file: 506-45-6.mol

Synonyms:22-hydroxydocosanoic acid;Phellonic acid;506-45-6;22-hydroxy-docosanoic acid;omega-hydroxy behenic acid;22-Hydroxydocosanoic acid (Omega-Hydroxybehenic acid);Phellonsaure;LMFA01050079;22-hydroxybehenic acid;omega-hydroxybehenic acid;omega-hydroxydocosanoic acid;SCHEMBL150882;CHEBI:76322;DTXSID40415255;IBPVZXPSTLXWCG-UHFFFAOYSA-N;PD077275;CS-0435126;C19623;E84032;Q27145882

Chemical Property of 22-Hydroxydocosanoic acid

Chemical Property:

• Vapor Pressure: 1E-11mmHg at 25°C
• Boiling Point: 491.6oC at 760 mmHg
• Flash Point: 265.2oC
• PSA: 57.53000
• Density: 0.929g/cm3
• LogP: 6.86530
• XLogP3: 7.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 21
• Exact Mass: 356.32904526
• Heavy Atom Count: 25
• Complexity: 266

Purity/Quality:

98.5% ^*data from raw suppliers

22-hydroxy Docosanoic Acid ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(CCCCCCCCCCC(=O)O)CCCCCCCCCCO
• Description: 22-hydroxy Docosanoic acid is a hydroxylated fatty acid that has been found in the suberin component of silver birch (B. pendula) outer bark as well as the leaves, roots, and wood of Q. ilex from Cala Violina and Colognole, Italy. [Matreya, LLC. Catalog No. 1818]
• Uses: 22-?Hydroxydocosanoic Acid is a lipophilic extract from Acacia dealbata which may be used in improving the hydrophobicity of suberin fatty acids.

Technology Process of 22-Hydroxydocosanoic acid

There total 17 articles about 22-Hydroxydocosanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

22-(tetrahydropyran-2-yloxy)docosanoic acid (96303-15-0) → 22-hydroxydocosanoic acid (506-45-6)

Guidance literature:

With toluene-4-sulfonic acid; In tetrahydrofuran; water; acetic acid; for 7h; Heating;

Reference yield: 98.0%

22-hydroxydocosa-10,12-diynoic acid → 22-hydroxydocosanoic acid (506-45-6)

Guidance literature:

With palladium on activated charcoal; hydrogen; In dichloromethane; at 20 ℃; for 16h; under 7500.75 Torr; Autoclave;

DOI:10.1002/anie.202105882

Reference yield: 53.0%

22-benzyloxydocosanoic acid (177177-92-3) → 22-hydroxydocosanoic acid (506-45-6)

Guidance literature:

With hydrogen; palladium-carbon; palladium; In ethanol;

upstream raw materials:

1,20-eicosanedicarboxylic acid monomethyl ester

Phellochrysein; Phloiorubein

22-(tetrahydropyran-2-yloxy)docosanoic acid

undec-10-yn-1-ol

Downstream raw materials:

22-Brom-docosansaeure

Refernces

• 1、 -. "DEPOLYMERIZATION EXTRACTION OF COMPOUNDS FROM BIRCH BARK". Page/Page column 34; 40-41. . Retrieved 2008/06/13.
• 2、 -. "Process of preparing ω-hydroxy acids". . . Retrieved 2008/06/13.