2-Methyl-6-acetylnaphthalene

Base Information

• Chemical Name: 2-Methyl-6-acetylnaphthalene
• CAS No.: 5156-83-2
• Molecular Formula: C13H12O
• Molecular Weight: 184.238
• Hs Code.: 2914399090
• Mol file: 5156-83-2.mol

Synonyms:6'-METHYL-2'-ACETONAPHTHONE;6-ACETYL-2-METHYLNAPHTHALENE;

Chemical Property of 2-Methyl-6-acetylnaphthalene

Chemical Property:

• Vapor Pressure: 0.000307mmHg at 25°C
• Melting Point: 70-71 °C
• Boiling Point: 184 °C
• PSA: 17.07000
• Density: 1.075±0.06 g/cm3(Predicted)
• LogP: 3.35080

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methyl-6-acetylnaphthalene

There total 15 articles about 2-Methyl-6-acetylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

acetyl fluoride (557-99-3) + 2-Methylnaphthalene (91-57-6,34468-07-0) → 6-methyl-2-acetonaphthone (5156-83-2)

Guidance literature:

With boron trifluoride; In dichloromethane; at 0 - 10 ℃; for 1h;

DOI:10.1021/jo00176a034

Reference yield: 28.0%

acetyl chloride (75-36-5) + 2-Methylnaphthalene (91-57-6,34468-07-0) → acetyl-8 methyl-2 naphtalene (41774-41-8) + 6-methyl-2-acetonaphthone (5156-83-2)

Guidance literature:

aluminium chloride; In ice-water; chloroform;

Reference yield:

acetyl chloride (75-36-5) + 2-Methylnaphthalene (91-57-6,34468-07-0) → 6-methyl-2-acetonaphthone (5156-83-2)

Guidance literature:

With aluminum (III) chloride; In nitrobenzene; at 0 - 5 ℃; for 1.5h;

upstream raw materials:

4,4-Dimethoxy-3-[1-p-tolyl-meth-(E)-ylidene]-pentan-2-one

acetyl chloride

2-Methylnaphthalene

acetyl fluoride

Downstream raw materials:

6-acetoxy-2-naphthoic acid

C₂₅H₂₈N₂O₂

(6-Methyl-2-naphthacyl)-benzoat

2,6-Naphthalenedicarboxylic acid

Refernces

• 1、 Guidotti, Matteo,Canaff, Christine,Coustard, Jean-Marie,Magnoux, Patrick,Guisnet, Michel. "Acetylation of aromatic compounds over H-BEA zeolite: The influence of the substituents on the reactivity and on the catalyst stability". . p. 375 - 383. Retrieved 2007/10/03.
• 2、 Friese, V.,Boos, A.,Bauch, H.-J.,Leistner, E.. "BIOSYNTHESIS OF AXENOMYCIN D: INCORPORATION OF 13C-LABELLED PRECURSORS INTO THE MENADIONE CHROMOPHORE, DESOXYSUGARS AND THE AXENOLIDE". . p. 613 - 622. Retrieved 2007/10/02.