Tetrahydro-2-methyl-2H-thiopyran

Base Information

• Chemical Name: Tetrahydro-2-methyl-2H-thiopyran
• CAS No.: 5161-16-0
• Molecular Formula: C6H12S
• Molecular Weight: 116.227
• Hs Code.: 2934999090
• Mol file: 5161-16-0.mol

Synonyms:2-methyl-thiane;2-methyl-tetrahydro-thiopyran;α-Methyl-pentamethylensulfid;2-methylthiane;2-Methyl-pentamethylensulfid;tetrahydro-2-methyl-2H-thiopyran;2H-Thiopyran, tetrahydro-2-methyl-;

Chemical Property of Tetrahydro-2-methyl-2H-thiopyran

Chemical Property:

• Vapor Pressure: 4.36mmHg at 25°C
• Melting Point: -58.14°C
• Refractive Index: 1.4881
• Boiling Point: 153.04°C
• PSA: 25.30000
• Density: 0.9381
• LogP: 2.29200

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Tetrahydro-2-methyl-2H-thiopyran

There total 5 articles about Tetrahydro-2-methyl-2H-thiopyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

2,5-dichloromethylthiophane (75937-65-4) → 2,5-dimethylthiacyclopentane (1551-31-1,5161-13-7,5161-14-8,57774-92-2) + 2-methyl-thiane (5161-16-0)

Guidance literature:

With diisobutylaluminium hydride; In toluene; at 80 ℃; for 2h;

Reference yield:

2-Methylpiperidin (109-05-7,3000-79-1) → 2-ethyltetrahydrothiophene (1551-32-2) + 2,5-dimethylthiacyclopentane (1551-31-1,5161-13-7,5161-14-8,57774-92-2) + 2-methyl-thiane (5161-16-0) + 1-hexene (592-41-6,25067-06-5) + 2-hexanethiol (1679-06-7) + trans-3-Hexene (13269-52-8)

Guidance literature:

With hydrogen sulfide; hydrogen; sulphidized nickel-tungsten; at 300 ℃; for 6h; under 35252.8 Torr; Product distribution;

Reference yield:

hex-5-ene-1-thiol (17651-39-7) → thiepane (4753-80-4) + 2-methyl-thiane (5161-16-0)

Guidance literature:

In hexane; at -65 ℃; Irradiation;

DOI:10.1016/S0040-4039(01)96771-1

upstream raw materials:

hex-5-ene-1-thiol

sulfure d'allyle et d'hexene-5 yle-1

sulfure de benzyle et d'hexene-5 yle-1

2,5-dichloromethylthiophane

Downstream raw materials:

4-Methyl-N-[2-methyl-tetrahydro-1λ⁴-thiopyran-(1Z)-ylidene]-benzenesulfonamide

4-Methyl-N-[(S)-2-methyl-tetrahydro-1λ⁴-thiopyran-(1Z)-ylidene]-benzenesulfonamide

1-(2,5-Dihydroxy-phenyl)-2-methyl-tetrahydro-thiopyranium; chloride

S-methyl-2-methylthianium iodide

Refernces

• 1、 Cerny, Mirko,Trka, Antonin. "FORMATION OF SULPHUR COMPOUNDS IN THE HYDRODENITROGENATION OF 2-METHYLQUINOLINE, 2-METHYLPIPERIDINE, INDOLE, AND ISOQUINOLINE ON A NICKEL-TUNGSTEN CATALYST IN THE PRESENCE OF HYDROGEN SULPHIDE". . p. 3413 - 3420. Retrieved 2007/10/02.
• 2、 Tolstikov, G. A.,Kantyukova, R. G.,Spirikhin, L. V.. "REACTION OF SULFUR HALIDES WITH UNSATURATED COMPOUNDS XV. 2,2'-DICHLORO SULFIDES IN REACTION WITH ORGANOALUMINUM COMPOUNDS". . p. 1210 - 1218. Retrieved 2007/10/02.