Ethynamine

Base Information

• Chemical Name: Ethynamine
• CAS No.: 52324-04-6
• Molecular Formula: C2H3N
• Molecular Weight: 41.0525
• Mol file: 52324-04-6.mol

Synonyms:

Chemical Property of Ethynamine

Chemical Property:

• PSA: 26.02000
• LogP: 0.23610

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethynamine

There total 2 articles about Ethynamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(aminomethylene)-3-methylisoxazol-5(4H)-one (127158-08-1) → propargylamine (52324-04-6) + acetonitrile (75-05-8,26809-02-9)

Guidance literature:

In gas; at 560 - 690 ℃; under 1E-05 - 0.0001 Torr; flash vacuum pyrolysis;

DOI:10.1021/ja00213a002

Reference yield:

4-(aminomethylene)-3-phenylisoxazol-5(4H)-one (99361-31-6) → propargylamine (52324-04-6) + benzonitrile (100-47-0)

Guidance literature:

In gas; at 560 - 690 ℃; under 1E-05 - 0.0001 Torr; flash vacuum pyrolysis;

DOI:10.1021/ja00213a002

Reference yield: 90.0%

BOC-glycine (4530-20-5) + propargylamine (52324-04-6) → tert-butyl (2-oxo-2-(prop-2-yn-1-ylamino)ethyl)carbamate (847490-49-7)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃;

DOI:10.1039/c2ob25774b

upstream raw materials:

4-(aminomethylene)-3-methylisoxazol-5(4H)-one

4-(aminomethylene)-3-phenylisoxazol-5(4H)-one

Downstream raw materials:

tert-butyl (2-oxo-2-(prop-2-yn-1-ylamino)ethyl)carbamate

[Cu(CF₃SO₃)(H₂O)(MeCN)(N-benzyl-bis(2-picolyl)amine)][CF₃SO₃]