2-iodoethanamine

Base Information

• Chemical Name: 2-iodoethanamine
• CAS No.: 52689-15-3
• Molecular Formula: C2H6IN
• Molecular Weight: 170.98000
• Mol file: 52689-15-3.mol

Synonyms:Ethanamine,2-iodo;

Chemical Property of 2-iodoethanamine

Chemical Property:

• PSA: 26.02000
• LogP: 1.08040

Purity/Quality:

99% ^*data from raw suppliers

2-iodoethanamine 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-iodoethanamine

There total 1 articles about 2-iodoethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanolamine (141-43-5) → 2-iodoethylamine (52689-15-3)

Guidance literature:

With water; hydrogen iodide; at 180 ℃;

DOI:10.1021/jo01151a025

Reference yield:

2-(4-fluorophenyl)-5-(piperidin-4-yl)-3-(pyridin-4-yl)-pyrrole (188343-78-4) + 2-iodoethylamine (52689-15-3) → 2-(4-(5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyrrol-2-yl)piperidin-1-yl)ethanamine

Guidance literature:

2-(4-fluorophenyl)-5-(piperidin-4-yl)-3-(pyridin-4-yl)-pyrrole; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃;

2-iodoethylamine; In N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2005.04.060

Reference yield:

2-iodoethylamine (52689-15-3) + 1-tert-butoxycarbonyl-4-(2-((methylsulfonyl)amino)phenyl)piperazine (444582-15-4) → 4-{2-[(2-amino-ethyl)-methanesulfonyl-amino]-phenyl}-piperazine-1-carboxylic acid tert-butyl ester (850998-10-6)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2005.01.060

upstream raw materials:

ethanolamine

Downstream raw materials:

N-benzyloxycarbonyl-2-iodo-ethylamine

4-{2-[(2-amino-ethyl)-methanesulfonyl-amino]-phenyl}-piperazine-1-carboxylic acid tert-butyl ester