ETHYL METHYLPHOSPHINATE

Base Information

• Chemical Name: ETHYL METHYLPHOSPHINATE
• CAS No.: 16391-07-4
• Molecular Formula: C3H9O2P
• Molecular Weight: 108.077
• Hs Code.: 2931900090
• European Community (EC) Number: 812-047-1
• DSSTox Substance ID: DTXSID10936886
• Wikidata: Q72495480
• Mol file: 16391-07-4.mol

Synonyms:Phosphinicacid, methyl-, ethyl ester (6CI,7CI,8CI,9CI);Ethoxymethylphosphine oxide;Ethyl hydrogen methylphosphonite;Ethyl methanephosphinate;Ethylmethanephosphonite;Ethyl methylphosphinate;Ethyl methylphosphonite;

Chemical Property of ETHYL METHYLPHOSPHINATE

Chemical Property:

• Vapor Pressure: 22.395mmHg at 25°C
• Boiling Point: 115.661 °C at 760 mmHg
• Flash Point: 36.579 °C
• PSA: 49.77000
• Density: 1.0511 g/cm3
• LogP: 1.12740
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 107.02619149
• Heavy Atom Count: 6
• Complexity: 52.8

Purity/Quality:

99% ^*data from raw suppliers

ETHYL METHYLPHOSPHINATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCO[P+](=O)C

Technology Process of ETHYL METHYLPHOSPHINATE

There total 7 articles about ETHYL METHYLPHOSPHINATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyldiethoxyphosphine (15715-41-0) → ethyl methylphosphinate (16391-07-4)

Guidance literature:

With water; at 22 ℃; for 17h;

DOI:10.1039/c6dt01264g

Reference yield: 98.6%

ethanol (64-17-5) + methyldichlorophosphane (676-83-5) → ethyl methylphosphinate (16391-07-4)

Guidance literature:

at 60 ℃; for 0.0333333h; Temperature; Flow reactor;

Reference yield: 93.3%

methylphosphonic acid dichloroanhydride (676-97-1) + ethanol (64-17-5) → ethyl methylphosphinate (16391-07-4)

Guidance literature:

With ammonia; In cyclohexane; at -10 ℃; for 1h;

upstream raw materials:

ethanol

methyldichlorophosphane

methyldibromophosphine

Ethyl N,N-Diethyl-P-methylphosphonamidite

Downstream raw materials:

(hydroxy-diphenyl-methyl)-methyl-phosphinic acid ethyl ester

glufosinate ammonium

3-(ethoxy-methyl-phosphinoyl)-3-hydroxy-piperidine-1-carboxylic acid benzyl ester

ethyl <3--1-hydroxypropyl>methylphosphinate

Refernces

• 1、 Kehler, Jan,Ebert, Bjarke,Dahl, Otto,Krogsgaard-Larsen, Povl. "Syntheses and GABA receptor binding properties of 4-amino-1-, 2-, and 3- hydroxybutylphosphinic acids". . p. 771 - 780. Retrieved 1999.
• 2、 Walter, Edward R. H.,Fox, Mark A.,Parker, David,Williams, J. A. Gareth. "Enhanced selectivity for Mg2+ with a phosphinate-based chelate: APDAP: versus APTRA". . p. 1879 - 1887. Retrieved 2018.
• 3、 -. "Preparation method of glufosinate ammonium intermediate methylphosphinic acid monoester". Paragraph 0055; 0057. . Retrieved 2018/07/15.