(Z)-2-Hydroxyimino-1,2-diphenylethanone

Base Information

• Chemical Name: (Z)-2-Hydroxyimino-1,2-diphenylethanone
• CAS No.: 574-16-3
• Molecular Formula: C14H11NO2
• Molecular Weight: 225.247
• Mol file: 574-16-3.mol

Synonyms:2-hydroxyimino-1,2-diphenylethan-1-one;HMS2744C11;benzil monooxime;1,2-diphenyl-1-hydroxyiminoethane-2-one;1,2-diphenylethane-1,2-dione monooxime;

Chemical Property of (Z)-2-Hydroxyimino-1,2-diphenylethanone

Chemical Property:

• PSA: 49.66000
• LogP: 2.74780

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (Z)-2-Hydroxyimino-1,2-diphenylethanone

There total 44 articles about (Z)-2-Hydroxyimino-1,2-diphenylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

benzil (134-81-6) → benzilmonoxime (574-15-2,574-16-3,14090-77-8,5351-34-8)

Guidance literature:

With hydroxylamine hydrochloride; silica gel; at 20 ℃; for 6h; regioselective reaction; Green chemistry;

Reference yield: 96.0%

phenyl benzyl ketone (451-40-1) → benzilmonoxime (574-15-2,574-16-3,14090-77-8,5351-34-8)

Guidance literature:

With hydrogenchloride; tert-Butyl thionitrate; In tetrahydrofuran; at 0 ℃; for 0.4h;

DOI:10.1016/S0040-4039(00)99137-8

Reference yield: 83.0%

benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) + 2-nitroacetophenone (614-21-1) → benzilmonoxime (574-15-2,574-16-3,14090-77-8,5351-34-8)

Guidance literature:

With trifluorormethanesulfonic acid; trifluoroacetic acid; In dichloromethane; at 0 ℃; for 0.333333h; Inert atmosphere;

DOI:10.1055/s-0029-1217036

upstream raw materials:

phenyl benzyl ketone

benzene

2-nitroacetophenone

benzil

Downstream raw materials:

phenyl-benzoinoxime

1,2-Diphenyl-ethane-1,2-dione dioxime

erythro-2-amino-1,2-diphenylethanol

benzonitrile

Refernces

• 1、 Plater, M. John,Harrison, William T. A.,Killah, Ross. "Potential photoacid generators based on oxime sulfonates". . p. 26 - 33. Retrieved 2019/06/03.
• 2、 Ghosh, Pranab,Subba, Raju. "Green and highly selective protocol for the synthesis of oximes". . p. 529 - 532. Retrieved 2013/11/06.