4-BroMo-2,3-dihydro-1H-indene

Base Information

• Chemical Name: 4-BroMo-2,3-dihydro-1H-indene
• CAS No.: 6134-53-8
• Molecular Formula: C9H9Br
• Molecular Weight: 197.074
• Hs Code.: 2903999090
• Mol file: 6134-53-8.mol

Synonyms:4-BROMOINDANE;4-Brom-indan;1H-Indene,4-bromo-2,3-dihydro;4-bromo-indan;

Chemical Property of 4-BroMo-2,3-dihydro-1H-indene

Chemical Property:

• Boiling Point: 118 °C(Press: 18 Torr)
• PSA: 0.00000
• Density: 1.462±0.06 g/cm3(Predicted)
• LogP: 2.93780
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Bromo-2,3-dihydro-1H-indene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BroMo-2,3-dihydro-1H-indene

There total 18 articles about 4-BroMo-2,3-dihydro-1H-indene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

INDANE (496-11-7) → 4-bromo-2,3-dihydro-1H-indene (6134-53-8)

Guidance literature:

With aluminum oxide; bromine; for 0.0166667h; Ambient temperature;

DOI:10.1080/00397919208021092

Reference yield: 85.0%

4-bromo-2,3-dihydroinden-1-one (15115-60-3) → 4-bromo-2,3-dihydro-1H-indene (6134-53-8)

Guidance literature:

With triethylsilane; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; at -20 - 20 ℃; for 2h;

Reference yield: 15.0%

4-aminoindan (32202-61-2) → 4-bromo-2,3-dihydro-1H-indene (6134-53-8)

Guidance literature:

4-aminoindan; With tetrafluoroboric acid; sodium nitrite; In water; for 0.333333h; Cooling with ice;

With copper(ll) bromide; In dimethyl sulfoxide; for 0.5h;

upstream raw materials:

INDANE

4-bromo-2,3-dihydroinden-1-one

2-fluoro-1-(3-iodopropyl)benzene

bromine

Downstream raw materials:

<4>Indanyl-o-tolyl-keton

<4>Indanyl-p-tolyl-keton

3-bromophthalic acid

2-(2,3-dihydro-1H-inden-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Refernces

• 1、 -. "INFLUENZA VIRUS REPLICATION INHIBITOR AND USES THEREOF". Paragraph 00190; 00317-00318. . Retrieved 2020/05/21.
• 2、 -. "NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS II". Page/Page column 110. . Retrieved 2015/03/13.