Benzenemethanol, 4-(heptyloxy)-

Base Information

• Chemical Name: Benzenemethanol, 4-(heptyloxy)-
• CAS No.: 61440-52-6
• Molecular Formula: C14H22O2
• Molecular Weight: 222.327
• Mol file: 61440-52-6.mol

Synonyms:4-heptyloxybenzyl alcohol;p-heptyloxybenzyl alcohol;4-Heptyloxy-benzylalkohol;

Chemical Property of Benzenemethanol, 4-(heptyloxy)-

Chemical Property:

• PSA: 29.46000
• LogP: 3.52810

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenemethanol, 4-(heptyloxy)-

There total 5 articles about Benzenemethanol, 4-(heptyloxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4-(n-heptyloxy)benzaldehyde (27893-41-0) → 4-heptyloxybenzyl alcohol (61440-52-6)

Guidance literature:

With sodium tetrahydroborate; sodium hydroxide; In water; at 35 ℃; for 1h; pH=12; Reagent/catalyst; Green chemistry;

DOI:10.1039/c5gc02621k

Reference yield:

4-heptyloxybenzoic acid (15872-42-1) → 4-heptyloxybenzyl alcohol (61440-52-6)

Guidance literature:

With hydrogenchloride; borane; In tetrahydrofuran; water;

Reference yield:

1-Bromoheptane (629-04-9) → 4-heptyloxybenzyl alcohol (61440-52-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2: sodium tetrahydroborate / methanol / 0 - 20 °C / Inert atmosphere

With sodium tetrahydroborate; potassium carbonate; In methanol; N,N-dimethyl-formamide; 1: |Williamson Ether Synthesis;

DOI:10.1016/j.bmc.2013.10.015

upstream raw materials:

4-(n-heptyloxy)benzaldehyde

4-heptyloxybenzoic acid

1-Bromoheptane

4-hydroxy-benzaldehyde

Downstream raw materials:

1-(bromomethyl)-4-(heptyloxy)benzene

p-Heptyloxybenzyl alcohol O-Methanesulfonate

4-(4'heptyloxybenzyloxy)benzoic acid

Refernces

• 1、 Du, Jianguo,Xu, Gang,Lin, Huikun,Wang, Guangwei,Tao, Minli,Zhang, Wenqin. "Highly efficient reduction of carbonyls, azides, and benzyl halides by NaBH4 in water catalyzed by PANF-immobilized quaternary ammonium salts". supporting information. p. 2726 - 2735. Retrieved 2016/05/24.
• 2、 -. "Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives". . . Retrieved 2008/06/13.