3-PHENYLTHIOPROPIONITRILE

Base Information

• Chemical Name: 3-PHENYLTHIOPROPIONITRILE
• CAS No.: 3055-87-6
• Molecular Formula: C9H9 N S
• Molecular Weight: 163.243
• Hs Code.: 2930909090
• Mol file: 3055-87-6.mol

Synonyms:Propionitrile,3-(phenylthio)- (6CI,7CI,8CI); 2-Cyanoethyl phenyl sulfide;3-(Phenylthio)propanenitrile; 3-(Phenylthio)propanonitrile;3-Phenylthiopropionitrile; NSC 2238

Chemical Property of 3-PHENYLTHIOPROPIONITRILE

Chemical Property:

• Vapor Pressure: 0.000814mmHg at 25°C
• Boiling Point: 305.6°Cat760mmHg
• Flash Point: 138.6°C
• PSA: 49.09000
• Density: 1.1g/cm³
• LogP: 2.69238

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-PHENYLTHIOPROPIONITRILE

There total 9 articles about 3-PHENYLTHIOPROPIONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

thiophenol (108-98-5) + acrylonitrile (107-13-1,25014-41-9) → 3-(phenylthio)propionitrile (3055-87-6)

Guidance literature:

triethylamine;

DOI:10.1021/jo00315a002

Reference yield: 98.0%

acrylonitrile (107-13-1,25014-41-9) + diphenyldisulfane (882-33-7) → 3-(phenylthio)propionitrile (3055-87-6)

Guidance literature:

diphenyldisulfane; With sodium tetrahydroborate; at 20 ℃; for 0.666667h; Inert atmosphere;

acrylonitrile; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.08.101

Reference yield: 87.0%

iodobenzene (591-50-4) + acrylonitrile (107-13-1,25014-41-9) → 3-(phenylthio)propionitrile (3055-87-6)

Guidance literature:

iodobenzene; With potassium phosphate; copper(II) ferrite; sulfur; at 80 ℃; for 10h; Green chemistry;

acrylonitrile; With iron; at 80 ℃; for 5h; Green chemistry;

DOI:10.1039/c5nj00867k

upstream raw materials:

thiophenol

acrylonitrile

bromopropionitrile

2-cyanoethyl(phenyl)sulfoxide

Downstream raw materials:

acide phenylthio-3 propanoique

3-benzenesulfonyl-propionitrile

3-(phenylsulfonyl)propanamide

chloro-2 thiophenyl-3 propionitrile

Refernces

• 1、 Liu, Jian,Kragh, Rasmus R.,Kamounah, Fadhil S.,Lee, Ji-Woong. "Extended Pummerer fragmentation mediated by carbon dioxide and cyanide". supporting information. . Retrieved 2020/10/30.
• 2、 -. "PARTICLES, COMPOSITIONS, AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS". Paragraph 0176. . Retrieved 2018/04/12.