Ethanamine, 2-(3-nitrophenoxy)-, monohydrochloride

Base Information

• Chemical Name: Ethanamine, 2-(3-nitrophenoxy)-, monohydrochloride
• CAS No.: 61711-97-5
• Molecular Formula: C8H10N2O3.ClH
• Molecular Weight: 218.64
• Mol file: 61711-97-5.mol

Synonyms:

Chemical Property of Ethanamine, 2-(3-nitrophenoxy)-, monohydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethanamine, 2-(3-nitrophenoxy)-, monohydrochloride

There total 7 articles about Ethanamine, 2-(3-nitrophenoxy)-, monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

N-(2-(3-nitrophenoxy)ethyl)phthalimide (58910-41-1) → 1-amino-2-(3-nitrophenoxy)ethane hydrochloride (61711-97-5)

Guidance literature:

With hydrogenchloride; In acetic acid; for 16h; Heating;

DOI:10.1021/jo00223a016

Reference yield:

N-(2-(3-nitrophenoxy)ethyl)phthalimide (58910-41-1) → 1-amino-2-(3-nitrophenoxy)ethane hydrochloride (61711-97-5) + benzene-1,2-dicarboxylic acid (88-99-3,73607-73-5)

Guidance literature:

With hydrogenchloride; acetic acid; In water; Heating;

DOI:10.1021/ja00534a055

Reference yield:

tert-butyl (2-(3-nitrophenoxy)ethyl)carbamate (246240-09-5) → 1-amino-2-(3-nitrophenoxy)ethane hydrochloride (61711-97-5)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃;

DOI:10.1021/acs.jcim.9b00802

upstream raw materials:

N-(2-(3-nitrophenoxy)ethyl)phthalimide

2-(3-nitrophenoxy)ethanol

sodium 3-nitrophenoxide

2-(3-nitrophenoxy)ethyl tosylate

Downstream raw materials:

tert-butyl (2-(3-nitrophenoxy)ethyl)carbamate

N-(2-hydroxyethyl)-3-nitroaniline

Refernces

• 1、 Wubbels, Gene G.,Halverson, Ann M.,Oxman, Joe D.,Bruyn, Van H. De. "Regioselectivity of Photochemical and Thermal Smiles Rearrangements and Related Reactions of β-(Nitrophenoxy)ethylamines". . p. 4499 - 4504. Retrieved 2007/10/02.