1-ALLYL-2(1H)-PYRIDINONE

Base Information

• Chemical Name: 1-ALLYL-2(1H)-PYRIDINONE
• CAS No.: 21997-30-8
• Molecular Formula: C8H9NO
• Molecular Weight: 135.166
• Hs Code.: 2933399090
• Mol file: 21997-30-8.mol

Synonyms:2(1H)-Pyridinone,1-(2-propenyl)- (9CI);2(1H)-Pyridone, 1-allyl- (6CI,7CI,8CI);1-Allyl-1H-pyridin-2-one;1-Allyl-2-pyridone;

Chemical Property of 1-ALLYL-2(1H)-PYRIDINONE

Chemical Property:

• Vapor Pressure: 0.00272mmHg at 25°C
• Refractive Index: 1.523
• Boiling Point: 286 °C at 760 mmHg
• Flash Point: 134.7 °C
• PSA: 22.00000
• Density: 1.041 g/cm³
• LogP: 1.03430

Purity/Quality:

99% ^*data from raw suppliers

1-Allyl-2(1H)-pyridinone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-ALLYL-2(1H)-PYRIDINONE

There total 13 articles about 1-ALLYL-2(1H)-PYRIDINONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-allyloxypyridine (5831-77-6) → 1-(prop-2-enyl)-1,2-dihydropyridine-2-one (21997-30-8)

Guidance literature:

With bis(tri-t-butylphosphine)palladium⁽⁰⁾; In xylene; at 80 ℃; for 2h; Further Variations:; Reagents; Temperatures; Solvents; reaction times; Product distribution;

DOI:10.1021/ol0346234

Reference yield: 95.0%

2-Pyridone (142-08-5,1199357-22-6) + allyl bromide (106-95-6) → 1-(prop-2-enyl)-1,2-dihydropyridine-2-one (21997-30-8)

Guidance literature:

2-Pyridone; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; Inert atmosphere; Schlenk technique;

allyl bromide; In tetrahydrofuran; hexane; at 70 ℃; for 18h; Temperature; Time; chemoselective reaction; Inert atmosphere;

DOI:10.1016/j.tet.2014.09.043

Reference yield: 86.0%

2-iodomethyl-2,3-dihydro[1,3]oxazolo[3,2-a]pyridinium triiodide (100219-88-3) → 1-(prop-2-enyl)-1,2-dihydropyridine-2-one (21997-30-8)

Guidance literature:

With triethylamine; In methanol; for 20h; Reflux;

DOI:10.1134/S1070363218120071

upstream raw materials:

2-Pyridone

allyl ethyl carbonate

2-methoxypyridine

allyl bromide

Downstream raw materials:

1-propylpyridin-2(1H)-one

Refernces

• 1、 Kim,Kalita,Sharutin,Senchurin,Belov. "Properties of 2-Iodomethyl-2,3-dihydro[1,3]oxazolo[3,2-a]pyridinium Triiodide". . p. 2498 - 2503. Retrieved 2019.
• 2、 Godha, Atul K.,Thiruvengadam, Jayaraman,Abhilash, Viswanadhan,Balgi, Prajwal,Narayanareddy,Vignesh, Kumaresan,Gadakh, Amol V.,Sathiyanarayanan,Ganesh, Sambasivam. "Environmentally benign nucleophilic substitution reaction of arylalkyl halides in water using CTAB as the inverse phase transfer catalyst". supporting information. p. 16041 - 16045. Retrieved 2019/10/28.